Description
system_update_altDatasheet
| SKU: | HDAB0256 |
| Size: | 100 µg |
| Clonality: | Monoclonal |
| Clone: | DMC388 |
| Synonyms: | ED1; EDA2 |
| Applications: | Flow Cyt |
| Recommended Dilution: | Flow Cyt 1:100 |
| Host Species: | Rabbit |
| Isotype: | Rabbit/Human Fc chimeric IgG1 |
| Reactivity: | Human |
| Purification Method: | Purified from cell culture supernatant by affinity chromatography |
| Formulation: | Powder |
| Buffer: | 1XPBS |
| Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Usage: | Research use only |
| Background: | The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. |