Anti-Dynamin 3 Antibody (CAB19260)
- SKU:
- CAB19260
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DNM3
- Synonyms:
- Dyna III
- Synonyms:
- DynaIII
- Synonyms:
- dynamin-3
- Research Area:
- Cell Biology
Description
| Product Name: | Dynamin 3 Rabbit mAb |
| Product Code: | CAB19260 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | DNM3, Dyna III, DynaIII, dynamin-3 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human Dynamin 3 . |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SH-SY5Y, Mouse testis, Mouse spinal cord, Mouse brain |
| Immunogen: | Recombinant protein of human Dynamin 3 . |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 26052 |
| Uniprot: | Q9UQ16 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 97kDa |
| Observed MW: | 100KDa |
| UniProt Protein Function: | DYN3: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within dendritic spine tips of the postsynaptic compartment and interacts with mGluR5 and Homer. May play a role in dendritic spine morphogenesis and remodeling. |
| UniProt Protein Details: | Protein type:Mitochondrial; Vesicle; EC 3.6.5.5; Microtubule-binding; Motility/polarity/chemotaxis; Hydrolase; Motor Chromosomal Location of Human Ortholog: 1q24.3 Cellular Component: dendritic spine; perinuclear region of cytoplasm; postsynaptic density Molecular Function:GTPase activity; protein binding Biological Process: endocytosis; filopodium formation; synaptogenesis |
| NCBI Summary: | This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| UniProt Code: | Q9UQ16 |
| NCBI GenInfo Identifier: | 190358934 |
| NCBI Gene ID: | 26052 |
| NCBI Accession: | Q9UQ16.4 |
| UniProt Secondary Accession: | Q9UQ16,O14982, O95555, Q1MTM8, Q5W129, Q6P2G1, Q9H0P3 Q9H548, Q9NQ68, Q9NQN6, A9Z1Y1, |
| UniProt Related Accession: | Q9UQ16 |
| Molecular Weight: | 62,824 Da |
| NCBI Full Name: | Dynamin-3 |
| NCBI Synonym Full Names: | dynamin 3 |
| NCBI Official Symbol: | DNM3 |
| NCBI Official Synonym Symbols: | Dyna III |
| NCBI Protein Information: | dynamin-3 |
| UniProt Protein Name: | Dynamin-3 |
| UniProt Synonym Protein Names: | Dynamin, testicular; T-dynamin |
| Protein Family: | Dynamin |
| UniProt Gene Name: | DNM3 |
| UniProt Entry Name: | DYN3_HUMAN |
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