Cell Biology Antibodies 7

Anti-DUSP15 Antibody (CAB16322)

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SKU:
CAB16322
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DUSP15 Antibody
Antibody SKU:CAB16322
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 10-90 of human DUSP15 (NP_542178.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:PC-3, A-375, Mouse kidney, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 10-90 of human DUSP15 (NP_542178.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PGLY LGNF IDAK DLDQ LGRN KITH IISI HESP QPLL QDIT YLRI PVAD TPEV PIKK HFKE CINF IHCC RLNG GNCL VHCF A
Gene ID:128853
Uniprot:Q9H1R2
Cellular Location:
Calculated MW:14kDa/25kDa/26kDa/31kDa
Observed MW:32kDa
Synonyms:DUSP15, C20orf57, VHY
Background:The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:DUSP15: belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:EC 3.1.3.16; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity; EC 3.1.3.48

Chromosomal Location of Human Ortholog: 20q11.21

Molecular Function:protein binding

Biological Process: positive regulation of JNK cascade; regulation of cell proliferation; transforming growth factor beta receptor signaling pathway

NCBI Summary:The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
UniProt Code:Q9H1R2
NCBI GenInfo Identifier:30316387
NCBI Gene ID:128853
NCBI Accession:Q9H1R2.4
UniProt Secondary Accession:Q9H1R2,Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24 A6NH79, A8MVC8,
UniProt Related Accession:Q9H1R2
Molecular Weight:14,721 Da
NCBI Full Name:Dual specificity protein phosphatase 15
NCBI Synonym Full Names:dual specificity phosphatase 15
NCBI Official Symbol:DUSP15  
NCBI Official Synonym Symbols:VHY; C20orf57  
NCBI Protein Information:dual specificity protein phosphatase 15
UniProt Protein Name:Dual specificity protein phosphatase 15
UniProt Synonym Protein Names:VH1-related member Y
Protein Family:Dual specificity protein phosphatase
UniProt Gene Name:DUSP15  
UniProt Entry Name:DUS15_HUMAN
Anti-DUSP15 Antibody (CAB16322)Western blot analysis of extracts of various cell lines, using DUSP15 antibody (CAB16322) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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