Epigenetics & Nuclear Signaling Antibodies 2
Anti-DNTTIP1 Antibody (CAB15558)
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- SKU:
- CAB15558
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-DNTTIP1 Antibody |
| Antibody SKU: | CAB15558 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human DNTTIP1 (NP_443183.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, Jurkat, HeLa, Mouse thymus, Mouse spleen, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human DNTTIP1 (NP_443183.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGAT GDAE QPRG PSGA ERGG LELG DAGA AGQL VLTN PWNI MIKH RQVQ RRGR RSQM TTSF TDPA ISMD LLRA VLQP SINE EIQT VFNK YMKF FQKA ALNV RDNV GEEV DAEQ LIQE ACRS CLEQ AKLL FSDG EKVI PRLT HELP GIKR GRQA EEEC AHRG SPLP KKRK GRPP GHIL SSDR AAAG MVWK PKSC EPIR REGP KWDP ARLN ESTT FVLG SRAN KALG MGGT RGRI YIKH PHLF KYAA DPQD KHWL AEQH HMRA TGGK MAYL LIEE DIRD LAAS DDYR GCLD LKLE ELKS FVLP SWMV EKMR KYME TLRT ENEH RAVE APPQ T |
| Gene ID: | 116092 |
| Uniprot: | Q9H147 |
| Cellular Location: | Nucleus |
| Calculated MW: | 37kDa |
| Observed MW: | 37kDa |
| Synonyms: | DNTTIP1, C20orf167, Tdif1, dJ447F3.4 |
| Background: |
| UniProt Protein Function: | DNTTIP1: Shown to enhance TdT activity, in vitro. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: histone deacetylase complex; nucleolus; nucleoplasm; nucleus Molecular Function:DNA binding; nucleosome binding; protein binding; protein homodimerization activity |
| NCBI Summary: | DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9H147 |
| NCBI GenInfo Identifier: | 26400504 |
| NCBI Gene ID: | 116092 |
| NCBI Accession: | Q9H147.2 |
| UniProt Secondary Accession: | Q9H147,Q96DE3, Q9BQP2, Q9H148, B2RA18, |
| UniProt Related Accession: | Q9H147 |
| Molecular Weight: | 37,013 Da |
| NCBI Full Name: | Deoxynucleotidyltransferase terminal-interacting protein 1 |
| NCBI Synonym Full Names: | deoxynucleotidyltransferase terminal interacting protein 1 |
| NCBI Official Symbol: | DNTTIP1 |
| NCBI Official Synonym Symbols: | Tdif1; C20orf167; dJ447F3.4 |
| NCBI Protein Information: | deoxynucleotidyltransferase terminal-interacting protein 1 |
| UniProt Protein Name: | Deoxynucleotidyltransferase terminal-interacting protein 1 |
| UniProt Synonym Protein Names: | Terminal deoxynucleotidyltransferase-interacting factor 1; TdIF1 |
| Protein Family: | Deoxynucleotidyltransferase terminal-interacting protein |
| UniProt Gene Name: | DNTTIP1 |
| UniProt Entry Name: | TDIF1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DNTTIP1 antibody (CAB15558) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5S. |
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