Anti-DNA2 Antibody (CAB9354)
- SKU:
- CAB9354
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-DNA2 Antibody (CAB9354) |
| Antibody SKU: | CAB9354 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting, Immunohistochemistry |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 811-1060 of human DNA2 (NP_001073918.2). |
| Application: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500 - 1:1000 IHC 1:20 - 1:50 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 811-1060 of human DNA2 (NP_001073918.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
| Isotype: | IgG |
| Sequence: | KRLE QNKS AVVQ LTVQ YRMN SKIM SLSN KLTY EGKL ECGS DKVA NAVI NLRH FKDV KLEL EFYA DYSD NPWL MGVF EPNN PVCF LNTD KVPA PEQV EKGG VSNV TEAK LIVF LTSI FVKA GCSP SDIG IIAP YRQQ LKII NDLL ARSI GMVE VNTV DKYQ GRDK SIVL VSFV RSNK DGTV GELL KDWR RLNV AITR AKHK LILL GCVP SLNC YPPL EKLL NHLN SEKL IIDL PSRE HESL CHIL GDFQ RE |
| Cellular Location: | Mitochondrion, Nucleus |
| Calculated MW: | 78kDa/93kDa/119kDa/120kDa |
| Observed MW: | 127kDa |
| Synonyms: | DNA2, DNA2L, hDNA2 |
| Background: | This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. |
 | Western blot analysis of extracts of Mouse liver, using DNA2 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 120s. |
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