Developmental Biology

Anti-DLX2 Antibody (CAB8410)

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SKU:
CAB8410
Product Type:
Antibody
Applications:
WB
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-DLX2 Antibody
Antibody SKU:CAB8410
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DLX2 (NP_004396.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DLX2 (NP_004396.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MTGV FDSL VADM HSTQ IAAS STYH QHQQ PPSG GGAG PGGN SSSS SSLH KPQE SPTL PVST ATDS SYYT NQQH PAGG GGGG GSPY AHMG SYQY QASG LNNV PYSA KSSY DLGY TAAY TSYA PYGT SSSP ANNE PEKE DLEP
Gene ID:1746
Uniprot:Q07687
Cellular Location:Nucleus
Calculated MW:23kDa/34kDa
Observed MW:39kDa
Synonyms:DLX2, TES-1, TES1
Background:Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
UniProt Protein Function:DLX2: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis. Belongs to the distal-less homeobox family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 2q32

Molecular Function:protein binding; transcription factor activity

Biological Process: brain development

NCBI Summary:Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. [provided by RefSeq, Jul 2008]
UniProt Code:Q07687
NCBI GenInfo Identifier:2506529
NCBI Gene ID:1746
NCBI Accession:Q07687.2
UniProt Secondary Accession:Q07687,B4DMK4, B7ZA14,
UniProt Related Accession:Q07687
Molecular Weight:23,021 Da
NCBI Full Name:Homeobox protein DLX-2
NCBI Synonym Full Names:distal-less homeobox 2
NCBI Official Symbol:DLX2  
NCBI Official Synonym Symbols:TES1; TES-1  
NCBI Protein Information:homeobox protein DLX-2
UniProt Protein Name:Homeobox protein DLX-2
Protein Family:Homeobox protein
UniProt Gene Name:DLX2  
UniProt Entry Name:DLX2_HUMAN
Anti-DLX2 Polyclonal Antibody (CAB8410)Western blot analysis of extracts of rat brain, using DLX2 antibody (CAB8410) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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