Cell Biology Antibodies 12
Anti-Dermatopontin Antibody (CAB8643)
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- SKU:
- CAB8643
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Dermatopontin Antibody |
| Antibody SKU: | CAB8643 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human DPT (NP_001928.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse uterus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human DPT (NP_001928.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QYGD YGYP YQQY HDYS DDGW VNLN RQGF SYQC PQGQ VIVA VRSI FSKK EGSD RQWN YACM PTPQ SLGE PTEC WWEE INRA GMEW YQTC SNNG LVAG FQSR YFES VLDR EWQF YCCR YSKR CPYS CWLT TEYP GHYG EEMD MISY NYDY YIRG ATTT FSAV ERDR QWKF IMCR MTEY DCEF ANV |
| Gene ID: | 1805 |
| Uniprot: | Q07507 |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
| Calculated MW: | 24kDa |
| Observed MW: | 24kDa |
| Synonyms: | DPT, TRAMP |
| Background: | Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. |
| UniProt Protein Function: | DPT: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation. Belongs to the dermatopontin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 1q12-q23 Cellular Component: extracellular matrix; extracellular space |
| NCBI Summary: | Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q07507 |
| NCBI GenInfo Identifier: | 27151769 |
| NCBI Gene ID: | 1805 |
| NCBI Accession: | Q07507.2 |
| UniProt Secondary Accession: | Q07507,Q8N4R2, Q9UIX8, A8K981, |
| UniProt Related Accession: | Q07507 |
| Molecular Weight: | 24,005 Da |
| NCBI Full Name: | Dermatopontin |
| NCBI Synonym Full Names: | dermatopontin |
| NCBI Official Symbol: | DPT |
| NCBI Official Synonym Symbols: | TRAMP |
| NCBI Protein Information: | dermatopontin |
| UniProt Protein Name: | Dermatopontin |
| UniProt Synonym Protein Names: | Tyrosine-rich acidic matrix protein; TRAMP |
| Protein Family: | Dermatopontin |
| UniProt Gene Name: | DPT |
| UniProt Entry Name: | DERM_HUMAN |
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