Cell Biology Antibodies 7
Anti-DEFB4A Antibody (CAB1643)
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- SKU:
- CAB1643
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DEFB4A Antibody |
| Antibody SKU: | CAB1643 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-64 of human DEFB4A (NP_004933.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-64 of human DEFB4A (NP_004933.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MRVL YLLF SFLF IFLM PLPG VFGG IGDP VTCL KSGA ICHP VFCP RRYK QIGT CGLP GTKC CKKP |
| Gene ID: | 1673 |
| Uniprot: | O15263 |
| Cellular Location: | Secreted |
| Calculated MW: | 7kDa |
| Observed MW: | Refer to figures |
| Synonyms: | DEFB4A, BD-2, DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1 |
| Background: | Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. |
| UniProt Protein Function: | defensin, beta 2: Has antibacterial activity (Potential). Belongs to the beta-defensin family. LAP/TAP subfamily. |
| UniProt Protein Details: | Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide Chromosomal Location of Human Ortholog: 8p23.1 Cellular Component: Golgi lumen; extracellular region Biological Process: G-protein coupled receptor protein signaling pathway; defense response to bacterium; innate immune response; immune response; chemotaxis |
| NCBI Summary: | Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014] |
| UniProt Code: | O15263 |
| NCBI GenInfo Identifier: | 3023383 |
| NCBI Gene ID: | 100289462 |
| NCBI Accession: | O15263.1 |
| UniProt Secondary Accession: | O15263,Q52LC0, |
| Molecular Weight: | 7,038 Da |
| NCBI Full Name: | Beta-defensin 4A |
| NCBI Synonym Full Names: | defensin, beta 4B |
| NCBI Official Symbol: | DEFB4B |
| NCBI Official Synonym Symbols: | DEFB4P |
| NCBI Protein Information: | beta-defensin 4B; defensin, beta 4, pseudogene |
| UniProt Protein Name: | Beta-defensin 4A |
| UniProt Synonym Protein Names: | Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1 |
| UniProt Gene Name: | DEFB4A |
| UniProt Entry Name: | DFB4A_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat lung using DEFB4A antibody (CAB1643) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse lung using DEFB4A antibody (CAB1643) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of A431 cells using DEFB4A antibody (CAB1643) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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