Cell Biology Antibodies 17
Anti-DDX6 Antibody (CAB9634)
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- SKU:
- CAB9634
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DDX6 Antibody |
| Antibody SKU: | CAB9634 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human DDX6 |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, C2C12 |
| Immunogen: | A synthesized peptide derived from human DDX6 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1656 |
| Uniprot: | P26196 |
| Cellular Location: | |
| Calculated MW: | 54kDa |
| Observed MW: | 54KDa |
| Synonyms: | HLR2, P54, RCK |
| Background: | This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] |
| UniProt Protein Function: | DDX6: an oncogenic ATP-dependent helicase of the DEAD box family. Interacts with argonaute proteins, Ago1 and Ago2, and is a general repressor of translation in human cells by miRNA-induced gene silencing. In the process of mRNA degradation, may play a role in mRNA decapping. |
| UniProt Protein Details: | Protein type:RNA processing; Oncoprotein; EC 3.6.4.13; Helicase; RNA-binding Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: intracellular membrane-bound organelle; membrane; stress granule; cytoplasm; cytosol Molecular Function:protein domain specific binding; protein binding; helicase activity; ATP binding; RNA helicase activity Biological Process: gene expression; cytoplasmic mRNA processing body assembly; mRNA catabolic process, deadenylation-dependent decay |
| NCBI Summary: | This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] |
| UniProt Code: | P26196 |
| NCBI GenInfo Identifier: | 116241327 |
| NCBI Gene ID: | 1656 |
| NCBI Accession: | P26196.2 |
| UniProt Secondary Accession: | P26196,P54823, |
| UniProt Related Accession: | P26196 |
| Molecular Weight: | 483 |
| NCBI Full Name: | Probable ATP-dependent RNA helicase DDX6 |
| NCBI Synonym Full Names: | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| NCBI Official Symbol: | DDX6 |
| NCBI Official Synonym Symbols: | P54; RCK; HLR2 |
| NCBI Protein Information: | probable ATP-dependent RNA helicase DDX6; DEAD box-6; oncogene RCK; DEAD box protein 6; ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD) |
| UniProt Protein Name: | Probable ATP-dependent RNA helicase DDX6 |
| UniProt Synonym Protein Names: | ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK |
| UniProt Gene Name: | DDX6 |
| UniProt Entry Name: | DDX6_HUMAN |
 | Western blot - DDX6 Rabbit mAb (CAB9634) |
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