Cell Biology Antibodies 17
Anti-DDAH2 Antibody (CAB4159)
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- SKU:
- CAB4159
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DDAH2 Antibody |
| Antibody SKU: | CAB4159 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human DDAH2 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, Mouse lung, Mouse brain, Mouse kidney, Rat brain, Rat kidney |
| Immunogen: | A synthesized peptide derived from human DDAH2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 23564 |
| Uniprot: | O95865 |
| Cellular Location: | |
| Calculated MW: | 30kDa |
| Observed MW: | 30KDa |
| Synonyms: | DDAH, DDAHII, G6a, HEL-S-277, NG30 |
| Background: | This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| UniProt Protein Function: | DDAH2: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. Belongs to the DDAH family. |
| UniProt Protein Details: | Protein type:EC 3.5.3.18; Apoptosis; Hydrolase Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: centrosome; mitochondrion; cytoplasm Molecular Function:amino acid binding; protein binding; dimethylargininase activity; catalytic activity Biological Process: positive regulation of nitric oxide biosynthetic process; citrulline metabolic process; arginine catabolic process; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; negative regulation of apoptosis |
| NCBI Summary: | This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| UniProt Code: | O95865 |
| NCBI GenInfo Identifier: | 6831529 |
| NCBI Gene ID: | 23564 |
| NCBI Accession: | O95865.1 |
| UniProt Related Accession: | O95865 |
| Molecular Weight: | ~ 30kDa |
| NCBI Full Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
| NCBI Synonym Full Names: | dimethylarginine dimethylaminohydrolase 2 |
| NCBI Official Symbol: | DDAH2 |
| NCBI Official Synonym Symbols: | G6a; DDAH; NG30; DDAHII; HEL-S-277 |
| NCBI Protein Information: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
| UniProt Protein Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
| UniProt Synonym Protein Names: | DDAHII; Dimethylargininase-2; Protein G6a; S-phase protein |
| Protein Family: | N(G),N(G)-dimethylarginine dimethylaminohydrolase |
| UniProt Gene Name: | DDAH2 |
| UniProt Entry Name: | DDAH2_HUMAN |
 | Western blot - DDAH2 Rabbit mAb (CAB4159) |
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