Cell Biology Antibodies 17
Anti-DDAH1 Antibody (CAB4591)
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- SKU:
- CAB4591
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DDAH
- Synonyms:
- DDAH-1
- Synonyms:
- DDAHI
- Synonyms:
- HEL-S-16
- Research Area:
- Cell Biology
Description
| Product Name: | DDAH1 Rabbit mAb |
| Product Code: | CAB4591 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | DDAH, DDAH-1, DDAHI, HEL-S-16 |
| Applications: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human DDAH1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | 293T, HepG2, U-251MG, Rat kidney |
| Immunogen: | A synthesized peptide derived from human DDAH1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 23576 |
| Uniprot: | O94760 |
| Calculated MW: | 37kDa |
| Observed MW: | 37KDa |
| UniProt Protein Function: | DDAH1: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. Belongs to the DDAH family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.5.3.18; Hydrolase Chromosomal Location of Human Ortholog: 1p22.3 Cellular Component: cytosol Molecular Function:catalytic activity; dimethylargininase activity Biological Process: citrulline metabolic process; nitric oxide mediated signal transduction; positive regulation of nitric oxide biosynthetic process; regulation of nitric-oxide synthase activity; regulation of systemic arterial blood pressure |
| NCBI Summary: | This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O94760 |
| NCBI GenInfo Identifier: | 6831528 |
| NCBI Gene ID: | 23576 |
| NCBI Accession: | O94760.3 |
| UniProt Secondary Accession: | O94760,Q5HYC8, Q86XK5, |
| UniProt Related Accession: | O94760 |
| Molecular Weight: | 31kDa |
| NCBI Full Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| NCBI Synonym Full Names: | dimethylarginine dimethylaminohydrolase 1 |
| NCBI Official Symbol: | DDAH1 |
| NCBI Official Synonym Symbols: | DDAH; DDAHI; DDAH-1; HEL-S-16 |
| NCBI Protein Information: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| UniProt Protein Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| UniProt Synonym Protein Names: | DDAHI; Dimethylargininase-1 |
| Protein Family: | N(G),N(G)-dimethylarginine dimethylaminohydrolase |
| UniProt Gene Name: | DDAH1 |
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