Cell Cycle Antibodies 1

Cyclin D2 Rabbit Polyclonal Antibody (CAB1773)

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SKU:
CAB1773
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle
Reactivity:
Human, Mouse, Rat
Synonyms:
MPPH3, KIAK0002, Cyclin D2
Research Use:
Cell Cycle
Frequently bought together:

Description

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Cyclin D2 Antibody (CAB1773)

The Cyclin D2 Antibody (CAB1773) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CCND2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable resource for studies in cancer biology and cell biology.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Cyclin D2 Antibody
SKU:CAB1773
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MELL CHEV DPVR RAVR DRNL LRDD RVLQ NLLT IEER YLPQ CSYF KCVQ KDIQ PYMR RMVA TWML EVCE EQKC EEEV FPLA MNYL DRFL AGVP TPKS HLQL LGAV CMFL ASKL KETS PLTA EKLC IYTD NSIK PQEL LEWE LVVL GKLK WNLA AVTP HDFI EHIL RKLP QQRE KLSL IRKH AQTF IALC ATDF KFAM YPPS MIAT GSVG AAIC GLQQ DEEV SSLT CDAL TELL AKIT NTDV DCLK ACQE QIEA VLLN SLQQ YRQD QRDG SKSE DELD QAST PTDV RDID L
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MPPH3, KIAK0002, Cyclin D2
Positive Sample:NIH/3T3, Mouse spleen, Rat lung
Cellular Localization:Cytoplasm, Membrane, Nucleus.
Calculated MW:33kDa
Observed MW:34kDa

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3).

Purification MethodAffinity purification
Gene ID894
RRIDAB_2763815
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Cyclin D2 Rabbit pAb (CAB1773) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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