Cell Biology Antibodies 6

Anti-CXCL6 Antibody (CAB16207)

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SKU:
CAB16207
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CXCL6 Antibody
Antibody SKU:CAB16207
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 38-114 of human CXCL6 (NP_002984.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:LO2, A-549, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 38-114 of human CXCL6 (NP_002984.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GPVS AVLT ELRC TCLR VTLR VNPK TIGK LQVF PAGP QCSK VEVV ASLK NGKQ VCLD PEAP FLKK VIQK ILDS GNKK N
Gene ID:6372
Uniprot:P80162
Cellular Location:
Calculated MW:11kDa
Observed MW:17kDa
Synonyms:CXCL6, CKA-3, GCP-2, GCP2, SCYB6
Background:
UniProt Protein Function:CXCL6: Chemotactic for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function:heparin binding; chemokine activity; CXCR chemokine receptor binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; defense response to bacterium; neutrophil mediated immunity; immune response; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; chemotaxis; signal transduction; inflammatory response; regulation of cell proliferation

UniProt Code:P80162
NCBI GenInfo Identifier:2851486
NCBI Gene ID:6372
NCBI Accession:P80162.4
UniProt Secondary Accession:P80162,Q4W5D4, B2R4X3,
UniProt Related Accession:P80162
Molecular Weight:11,897 Da
NCBI Full Name:C-X-C motif chemokine 6
NCBI Synonym Full Names:chemokine (C-X-C motif) ligand 6
NCBI Official Symbol:CXCL6  
NCBI Official Synonym Symbols:GCP2; CKA-3; GCP-2; SCYB6  
NCBI Protein Information:C-X-C motif chemokine 6; chemokine alpha 3; small-inducible cytokine B6; granulocyte chemotactic protein 2; Small inducible cytokine subfamily B (Cys-X-Cys), member b; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)
UniProt Protein Name:C-X-C motif chemokine 6
UniProt Synonym Protein Names:Chemokine alpha 3; CKA-3; Granulocyte chemotactic protein 2; GCP-2; Small-inducible cytokine B6Cleaved into the following 3 chains:Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
UniProt Gene Name:CXCL6  
UniProt Entry Name:CXCL6_HUMAN
Anti-CXCL6 Antibody (CAB16207)Western blot analysis of extracts of various cell lines, using CXCL6 antibody (CAB16207) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-CXCL6 Antibody (CAB16207)Western blot analysis of extracts of Mouse kidney, using CXCL6 antibody (CAB16207) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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