Epigenetics & Nuclear Signaling Antibodies 3

Anti-CREBZF Antibody (CAB3477)

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SKU:
CAB3477
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-CREBZF Antibody
Antibody SKU:CAB3477
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human CREBZF (NP_001034707.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, 293T, HeLa, U-87MG, K-562, Mouse brain, Mouse heart, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human CREBZF (NP_001034707.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRHS LTKL LAAS GSNS PTRS ESPE PAAT CSLP SDLT RAAA GEEE TAAA GSPG RKQQ FGDE GELE AGRG SRGG VAVR APSP EEME EEAI ASLP GEET EDMD FLSG LELA DLLD PRQP DWHL DPGL SSPG PLSS SGGG SDSG GLWR GDDD DEAA AAEM QRFS DLLQ RLLN GIGG CSSS SDSG SAEK RRRK SPGG GGGG GSGN DNNQ AATK SPRK AAAA AARL NRLK KKEY VMGL ESRV RGLA AENQ ELRA ENRE LGKR VQAL QEES RYLR AVLA NETG LARL LSRL SGVG LRLT TSLF RDSP AGDH DYAL PVGK QKQD LLEE DDSA GGVC LHVD KDKV SVEF CSAC ARKA SSSL KM
Gene ID:58487
Uniprot:Q9NS37
Cellular Location:Nucleus
Calculated MW:37kDa
Observed MW:60kDa
Synonyms:CREBZF, SMILE, ZF
Background:
UniProt Protein Function:CREBZF: Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1- dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. Belongs to the bZIP family. ATF subfamily.
UniProt Protein Details:

Protein type:Transcription factor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 11q14

Cellular Component: nucleus

Molecular Function:identical protein binding; protein binding

Biological Process: negative regulation of gene expression, epigenetic; negative regulation of transcription, DNA-dependent; regulation of transcription factor activity; response to virus; transcription, DNA-dependent

UniProt Code:Q9NS37
NCBI GenInfo Identifier:251757415
NCBI Gene ID:58487
NCBI Accession:Q9NS37.2
UniProt Secondary Accession:Q9NS37,Q0P5U9, Q52LT3, B2R8Q9,
UniProt Related Accession:Q9NS37
Molecular Weight:37,134 Da
NCBI Full Name:CREB/ATF bZIP transcription factor
NCBI Synonym Full Names:CREB/ATF bZIP transcription factor
NCBI Official Symbol:CREBZF  
NCBI Official Synonym Symbols:ZF; SMILE  
NCBI Protein Information:CREB/ATF bZIP transcription factor
UniProt Protein Name:CREB/ATF bZIP transcription factor
UniProt Synonym Protein Names:Host cell factor-binding transcription factor Zhangfei; HCF-binding transcription factor Zhangfei
Protein Family:CREB/ATF bZIP transcription factor
UniProt Gene Name:CREBZF  
UniProt Entry Name:ZHANG_HUMAN
Anti-CREBZF Antibody (CAB3477)Western blot analysis of extracts of various cell lines, using CREBZF antibody (CAB3477) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 1s.
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