Name: Anti-CREB5 Antibody (CAB14635)
Brand: Epigenetics & Nuclear Signaling Antibodies 3
SKU: CAB14635
Availability: OutOfStock

Antibody Name:	Anti-CREB5 Antibody
Antibody SKU:	CAB14635
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 210-330 of human CREB5 (NP_878902.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Rat
Positive Samples:	293T, HeLa, MCF7

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 210-330 of human CREB5 (NP_878902.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	HPAA MSNG NMNT MGHM MEMM GSRQ DQTP HHHM HSHP HQHQ TLPP HHPY PHQH QHPA HHPH PQPH HQQN HPHH HSHS HLHA HPAH HQTS PHPP LHTG NQAQ VSPA TQQM QPTQ TIQP PQPT G
Gene ID:	9586
Uniprot:	Q02930
Cellular Location:	Nucleus
Calculated MW:	41kDa/53kDa/56kDa
Observed MW:	57kDa

Synonyms:

CREB5, CRE-BPA, CREB-5

Background:

The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt Protein Function:	CREB5: Binds to the cAMP response element and activates transcription. Belongs to the bZIP family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:DNA-binding; Transcription factor; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 7p15.1 Cellular Component: nucleus Molecular Function:protein binding; sequence-specific DNA binding; metal ion binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; fat cell differentiation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
NCBI Summary:	The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Code:	Q02930
NCBI GenInfo Identifier:	334302918
NCBI Gene ID:	9586
NCBI Accession:	Q02930.3
UniProt Secondary Accession:	Q02930,Q05886, Q06246, Q75N02, Q86UJ9, A8KA51, B4DU13 B5BUH3, C9JK47,
UniProt Related Accession:	Q02930
Molecular Weight:	41,161 Da
NCBI Full Name:	Cyclic AMP-responsive element-binding protein 5
NCBI Synonym Full Names:	cAMP responsive element binding protein 5
NCBI Official Symbol:	CREB5
NCBI Official Synonym Symbols:	CRE-BPA
NCBI Protein Information:	cyclic AMP-responsive element-binding protein 5; CREB-5; H_GS165L15.1; cAMP-responsive element-binding protein 5; cAMP response element binding protein CRE-Bpa; cAMP response element-binding protein CRE-BPa; cAMP responsive element binding protein 5 isoform alpha
UniProt Protein Name:	Cyclic AMP-responsive element-binding protein 5
UniProt Synonym Protein Names:	CRE-BPa
Protein Family:	Cyclic AMP-responsive element-binding protein
UniProt Gene Name:	CREB5
UniProt Entry Name:	CREB5_HUMAN

Western blot analysis of extracts of various cell lines, using CREB5 antibody (CAB14635) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

Antibodies

CREB5 Antibody (PACO08594)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)