Cell Biology Antibodies 1
Anti-CPD Antibody (CAB10208)
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- SKU:
- CAB10208
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CPD Antibody |
| Antibody SKU: | CAB10208 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 860-1100 of human CPD (NP_001295.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, HeLa, DU145, A-549, Mouse lung, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 860-1100 of human CPD (NP_001295.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SEGA IQVN FTLV RSST DSNN ESKK GKGA SSST NDAS DPTT KEFE TLIK DLSA ENGL ESLM LRSS SNLA LALY RYHS YKDL SEFL RGLV MNYP HITN LTNL GQST EYRH IWSL EISN KPNV SEPE EPKI RFVA GIHG NAPV GTEL LLAL AEFL CLNY KKNP AVTQ LVDR TRIV IVPS LNPD GRER AQEK DCTS KIGQ TNAR GKDL DTDF TNNA SQPE TKAI IENL IQKQ DFSL SVAL DGGS M |
| Gene ID: | 1362 |
| Uniprot: | O75976 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 126kDa/152kDa |
| Observed MW: | 200kDa |
| Synonyms: | CPD, GP180 |
| Background: | The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. |
| UniProt Protein Function: | CPD: The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:EC 3.4.17.22; Protease; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: extracellular space; membrane; nucleus; trans-Golgi network Molecular Function:metallocarboxypeptidase activity Biological Process: peptide metabolic process; protein processing |
| NCBI Summary: | The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75976 |
| NCBI GenInfo Identifier: | 115502368 |
| NCBI Gene ID: | 1362 |
| NCBI Accession: | O75976.2 |
| UniProt Secondary Accession: | O75976,O15377, Q86SH9, Q86XE6, B7Z7T9, B7ZAU4, F5GZH6 |
| UniProt Related Accession: | O75976 |
| Molecular Weight: | 126,487 Da |
| NCBI Full Name: | Carboxypeptidase D |
| NCBI Synonym Full Names: | carboxypeptidase D |
| NCBI Official Symbol: | CPD |
| NCBI Official Synonym Symbols: | GP180 |
| NCBI Protein Information: | carboxypeptidase D |
| UniProt Protein Name: | Carboxypeptidase D |
| UniProt Synonym Protein Names: | Metallocarboxypeptidase D; gp180 |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPD |
| UniProt Entry Name: | CBPD_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CPD antibody (CAB10208) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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