The Factor H Monoclonal Antibody (CAB8798) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in mice, is specifically reactive with human samples and has been validated for use in various immunoassays such as Western blot and ELISA.Complement factor H is a critical player in the regulation of the complement system, which is a major component of the immune response. Dysregulation of complement factor H is associated with various diseases, including autoimmune disorders and inflammatory conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
Factor H Monoclonal Antibody
SKU:
CAB8798
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC1306
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method
Affinity purification
Gene ID
3075
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from BxPC-3 cells, using Complement factor H Rabbit mAb (CAB8798) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
