Cell Biology Antibodies 10
Anti-COL10A1 Antibody (CAB6889)
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- SKU:
- CAB6889
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-COL10A1 Antibody |
| Antibody SKU: | CAB6889 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 521-680 of human COL10A1 (NP_000484.2). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:100 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 521-680 of human COL10A1 (NP_000484.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPEG FIKA GQRP SLSG TPLV SANQ GVTG MPVS AFTV ILSK AYPA IGTP IPFD KILY NRQQ HYDP RTGI FTCQ IPGI YYFS YHVH VKGT HVWV GLYK NGTP VMYT YDEY TKGY LDQA SGSA IIDL TEND QVWL QLPN AESN GLYS SEYV HSSF SGFL VAPM |
| Gene ID: | 1300 |
| Uniprot: | Q03692 |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
| Calculated MW: | 66kDa |
| Observed MW: |
| Synonyms: | COL10A1 |
| Background: | This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). |
| UniProt Protein Function: | Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage. |
| NCBI Summary: | This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q03692 |
| NCBI GenInfo Identifier: | 2506306 |
| NCBI Gene ID: | 1300 |
| NCBI Accession: | Q03692.2 |
| UniProt Secondary Accession: | Q03692,A1L4P2, |
| UniProt Related Accession: | Q03692 |
| Molecular Weight: | 66,158 Da |
| NCBI Full Name: | Collagen alpha-1(X) chain |
| NCBI Synonym Full Names: | collagen type X alpha 1 chain |
| NCBI Official Symbol: | COL10A1 |
| NCBI Protein Information: | collagen alpha-1(X) chain |
| UniProt Protein Name: | Collagen alpha-1(X) chain |
| Protein Family: | Collagen |
| UniProt Gene Name: | COL10A1 |
| UniProt Entry Name: | COAA1_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat lung using COL10A1 antibody (CAB6889) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human liver using COL10A1 antibody (CAB6889) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using COL10A1 antibody (CAB6889) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse lung using COL10A1 antibody (CAB6889) at dilution of 1:100 (40x lens). |
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