KO Validated Antibodies 2

Anti-CNPY2 Antibody (CAB20002)[KO Validated]

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SKU:
CAB20002
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CNPY2 Antibody [KO Validated]
Antibody SKU:CAB20002
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human CNPY2.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T
Immunogen:Recombinant protein of human CNPY2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:10330
Uniprot:Q9Y2B0
Cellular Location:Endoplasmic reticulum
Calculated MW:9kDa/20kDa
Observed MW:16KDa
Anti-CNPY2 Antibody [KO Validated] (CAB20002)Western blot analysis of extracts from normal (control) and CNPY2 knockout (KO) 293T cells, using CNPY2 antibody (CAB20002) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Synonyms:CNPY2, HP10390, MSAP, TMEM4, ZSIG9
Background:
UniProt Protein Function:TMEM4: Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Endoplasmic reticulum; Membrane protein, integral; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: endoplasmic reticulum; integral to plasma membrane

Molecular Function:protein binding

Biological Process: enzyme linked receptor protein signaling pathway; positive regulation of low-density lipoprotein receptor biosynthetic process; tissue development

UniProt Code:Q9Y2B0
NCBI GenInfo Identifier:50401205
NCBI Gene ID:10330
NCBI Accession:Q9Y2B0.1
UniProt Secondary Accession:Q9Y2B0,Q9UHE9, B2R7B9,
UniProt Related Accession:Q9Y2B0
Molecular Weight:21kDa
NCBI Full Name:Protein canopy homolog 2
NCBI Synonym Full Names:canopy FGF signaling regulator 2
NCBI Official Symbol:CNPY2  
NCBI Official Synonym Symbols:MSAP; TMEM4; ZSIG9; HP10390  
NCBI Protein Information:protein canopy homolog 2
UniProt Protein Name:Protein canopy homolog 2
UniProt Synonym Protein Names:MIR-interacting saposin-like protein; Putative secreted protein Zsig9; Transmembrane protein 4
Protein Family:Protein canopy
UniProt Gene Name:CNPY2  
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