Cell Biology Antibodies 2

Anti-CNPY2 Antibody (CAB12197)

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SKU:
CAB12197
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CNPY2 Antibody
Antibody SKU:CAB12197
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human CNPY2 (NP_055070.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:BxPC-3, SGC-7901, HeLa, HepG2, Mouse liver, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human CNPY2 (NP_055070.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKGW GWLA LLLG ALLG TAWA RRSQ DLHC GACR ALVD ELEW EIAQ VDPK KTIQ MGSF RINP DGSQ SVVE VPYA RSEA HLTE LLEE ICDR MKEY GEQI DPST HRKN YVRV VGRN GESS ELDL QGIR IDSD ISGT LKFA CESI VEEY EDEL IEFF SREA DNVK DKLC SKRT DLCD HALH ISHD EL
Gene ID:10330
Uniprot:Q9Y2B0
Cellular Location:Endoplasmic reticulum
Calculated MW:9kDa/20kDa
Observed MW:21kDa
Synonyms:CNPY2, HP10390, MSAP, TMEM4, ZSIG9
Background:
UniProt Protein Function:TMEM4: Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Endoplasmic reticulum; Membrane protein, integral; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: endoplasmic reticulum; integral to plasma membrane

Molecular Function:protein binding

Biological Process: enzyme linked receptor protein signaling pathway; positive regulation of low-density lipoprotein receptor biosynthetic process; tissue development

UniProt Code:Q9Y2B0
NCBI GenInfo Identifier:50401205
NCBI Gene ID:10330
NCBI Accession:Q9Y2B0.1
UniProt Secondary Accession:Q9Y2B0,Q9UHE9, B2R7B9,
UniProt Related Accession:Q9Y2B0
Molecular Weight:21kDa
NCBI Full Name:Protein canopy homolog 2
NCBI Synonym Full Names:canopy FGF signaling regulator 2
NCBI Official Symbol:CNPY2  
NCBI Official Synonym Symbols:MSAP; TMEM4; ZSIG9; HP10390  
NCBI Protein Information:protein canopy homolog 2
UniProt Protein Name:Protein canopy homolog 2
UniProt Synonym Protein Names:MIR-interacting saposin-like protein; Putative secreted protein Zsig9; Transmembrane protein 4
Protein Family:Protein canopy
UniProt Gene Name:CNPY2  
Anti-CNPY2 Antibody (CAB12197)Western blot analysis of extracts of various cell lines, using CNPY2 antibody (CAB12197) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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system_update_altDatasheetHuman CNPY2 Recombinant Protein CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migr