Cell Death Antibodies 1
Anti-CLPTM1L Antibody (CAB10468)
- SKU:
- CAB10468
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Antibody Name: | Anti-CLPTM1L Antibody |
Antibody SKU: | CAB10468 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-280 of human CLPTM1L (NP_110409.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-280 of human CLPTM1L (NP_110409.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | YTRP CSGD ANCI QPYL ARRP KLQL SVYT TTRS HLGA ENNI DLVL NVED FDVE SKFE RTVN VSVP KKTR NNGT LYAY IFLH HAGV LPWH DGKQ VHLV SPLT TYMV PKPE EINL LTGE SDTQ QIEA EKKP TSAL DEPV SHWR PRLA LNVM ADNF VFDG SSLP ADVH RYMK MIQL GKTV HYLP ILFI DQLS NRVK DLMV INRS TTEL PLTV SYDK VSLG RLRF WIHM QDAV YSLQ QFGF SEKD ADEV KGIF V |
Gene ID: | 81037 |
Uniprot: | Q96KA5 |
Cellular Location: | Membrane, Multi-pass membrane protein |
Calculated MW: | 58kDa/62kDa |
Observed MW: | Refer to figures |
Synonyms: | CLPTM1L, CRR9 |
Background: | The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. |
UniProt Protein Function: | CLPTM1L: Enhances cisplatin-mediated apoptosis, when overexpressed. Belongs to the CLPTM1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: membrane |
NCBI Summary: | The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015] |
UniProt Code: | Q96KA5 |
NCBI GenInfo Identifier: | 74732209 |
NCBI Gene ID: | 81037 |
NCBI Accession: | Q96KA5.1 |
UniProt Secondary Accession: | Q96KA5,Q658W6, Q7LG29, Q96AZ0, Q9H3N4, D3DTC1, |
UniProt Related Accession: | Q96KA5 |
Molecular Weight: | 58,356 Da |
NCBI Full Name: | Cleft lip and palate transmembrane protein 1-like protein |
NCBI Synonym Full Names: | CLPTM1 like |
NCBI Official Symbol: | CLPTM1L |
NCBI Official Synonym Symbols: | CRR9 |
NCBI Protein Information: | cleft lip and palate transmembrane protein 1-like protein |
UniProt Protein Name: | Cleft lip and palate transmembrane protein 1-like protein |
UniProt Synonym Protein Names: | Cisplatin resistance-related protein 9; CRR9p |
Protein Family: | Cleft lip and palate transmembrane protein 1-like protein |
UniProt Gene Name: | CLPTM1L |
UniProt Entry Name: | CLP1L_HUMAN |
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