Anti-Chromogranin B Antibody (CAB3517)
- SKU:
- CAB3517
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SCG1
- Research Area:
- Cell Biology
Description
| Product Name: | Chromogranin B Rabbit mAb |
| Product Code: | CAB3517 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | SCG1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Chromogranin B |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, PC-12, BxPC-3, SH-SY5Y, Mouse brain |
| Immunogen: | A synthesized peptide derived from human Chromogranin B |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1114 |
| Uniprot: | P05060 |
| Calculated MW: | 125kDa |
| Observed MW: | 110KDa |
| UniProt Protein Function: | CHGB: a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20p12.3 Cellular Component: extracellular region; secretory granule Molecular Function:protein binding; hormone activity |
| NCBI Summary: | This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009] |
| UniProt Code: | P05060 |
| NCBI GenInfo Identifier: | 311033509 |
| NCBI Gene ID: | 1114 |
| NCBI Accession: | P05060.2 |
| UniProt Secondary Accession: | P05060,Q59EU9, Q6IBS6, Q9BQV6, Q9UC25, Q9UJA6, A8K021 |
| UniProt Related Accession: | P05060 |
| Molecular Weight: | 78kDa |
| NCBI Full Name: | Secretogranin-1 |
| NCBI Synonym Full Names: | chromogranin B (secretogranin 1) |
| NCBI Official Symbol: | CHGB |
| NCBI Official Synonym Symbols: | SCG1 |
| NCBI Protein Information: | secretogranin-1; cgB; sgI; chromogranin-B; secretogranin B; secretogranin I |
| UniProt Protein Name: | Secretogranin-1 |
| UniProt Synonym Protein Names: | Chromogranin-B; CgB; Secretogranin I; SgI |
| Protein Family: | Secretogranin |
| UniProt Gene Name: | CHGB |
| UniProt Entry Name: | SCG1_HUMAN |
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