Epigenetics & Nuclear Signaling Antibodies 3
Anti-CGGBP1 Antibody (CAB4231)
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- SKU:
- CAB4231
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-CGGBP1 Antibody |
| Antibody SKU: | CAB4231 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human CGGBP1 (NP_003654.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | Raji, HeLa, 293T, Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human CGGBP1 (NP_003654.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MERF VVTA PPAR NRSK TALY VTPL DRVT EFGG ELHE DGGK LFCT SCNV VLNH VRKS AISD HLKS KTHT KRKA EFEE QNVR KKQR PLTA SLQC NSTA QTEK VSVI QDFV KMCL EANI PLEK ADHP AVRA FLSR HVKN GGSI PKSD QLRR AYLP DGYE NENQ LLNS QDC |
| Gene ID: | 8545 |
| Uniprot: | Q9UFW8 |
| Cellular Location: | Nucleus |
| Calculated MW: | 18kDa |
| Observed MW: | 20kDa |
| Synonyms: | CGGBP1, CGGBP, p20-CGGBP |
| Background: |
| UniProt Protein Function: | CGGBP1: Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter. |
| UniProt Protein Details: | Protein type:Transcription regulation Chromosomal Location of Human Ortholog: 3p11.1 Cellular Component: nucleoplasm; nucleus Molecular Function:double-stranded DNA binding; protein binding Biological Process: negative regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9UFW8 |
| NCBI GenInfo Identifier: | 116243045 |
| NCBI Gene ID: | 8545 |
| NCBI Accession: | Q9UFW8.2 |
| UniProt Secondary Accession: | Q9UFW8,O15183, D3DU38, |
| UniProt Related Accession: | Q9UFW8 |
| Molecular Weight: | 18,820 Da |
| NCBI Full Name: | CGG triplet repeat-binding protein 1 |
| NCBI Synonym Full Names: | CGG triplet repeat binding protein 1 |
| NCBI Official Symbol: | CGGBP1 |
| NCBI Official Synonym Symbols: | CGGBP; p20-CGGBP |
| NCBI Protein Information: | CGG triplet repeat-binding protein 1 |
| UniProt Protein Name: | CGG triplet repeat-binding protein 1 |
| UniProt Synonym Protein Names: | 20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein |
| Protein Family: | CGG triplet repeat-binding protein |
| UniProt Gene Name: | CGGBP1 |
| UniProt Entry Name: | CGBP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CGGBP1 antibody (CAB4231) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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