Signal Transduction Antibodies 3

Anti-CGB5 Antibody (CAB6486)

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SKU:
CAB6486
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-CGB5 Antibody
Antibody SKU:CAB6486
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-165 of human CGB5 (NP_000728.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:MCF7, Jurkat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-165 of human CGB5 (NP_000728.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ASKE PLRP RCRP INAT LAVE KEGC PVCI TVNT TICA GYCP TMTR VLQG VLPA LPQV VCNY RDVR FESI RLPG CPRG VNPV VSYA VALS CQCA LCRR STTD CGGP KDHP LTCD DPRF QDSS SSKA PPPS LPSP SRLP GPSD TPIL PQ
Gene ID:93659
Uniprot:P0DN86
Cellular Location:Secreted
Calculated MW:18kDa
Observed MW:20kDa
Synonyms:CGB5, CGB, HCG, hCGB
Background:This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
UniProt Protein Function:Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
NCBI Summary:This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
UniProt Code:P0DN86
NCBI GenInfo Identifier:1027923599
NCBI Gene ID:1082
NCBI Accession:P0DN86.1
UniProt Related Accession:P0DN86
Molecular Weight:
NCBI Full Name:Choriogonadotropin subunit beta 3
NCBI Synonym Full Names:chorionic gonadotropin subunit beta 3
NCBI Official Symbol:CGB3  
NCBI Official Synonym Symbols:CGB; CGB5; CGB7; CGB8; hCGB  
NCBI Protein Information:choriogonadotropin subunit beta 3
UniProt Protein Name:Choriogonadotropin subunit beta 3
UniProt Synonym Protein Names:Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotropin chain beta
UniProt Gene Name:CGB3  
Anti-CGB5 Antibody (CAB6486)Western blot analysis of extracts of various cell lines, using CGB5 antibody (CAB6486) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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