Cell Biology Antibodies 12

Anti-CEP83 Antibody (CAB8491)

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SKU:
CAB8491
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CEP83 Antibody
Antibody SKU:CAB8491
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 34-260 of human CEP83 (NP_057206.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HT-29, Mouse lung, Mouse spleen, Mouse thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 34-260 of human CEP83 (NP_057206.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MLID ERLR CEHH KANY QTLK AEHT RLQN EHVK LQNE LKHL FNEK QTQQ EKLQ LLLE ELRG ELVE KTKD LEEM KLQI LTPQ KLEL LRAQ IQQE LETP MRER FRNL DEEV EKYR AVYN KLRY EHTF LKSE FEHQ KEEY ARIL DEGK IKYE SEIA RLEE DKEE LRNQ LLNV DLTK DSKR VEQL AREK VYLC QKLK GLEA EVAE LKAE KENS EAQV ENAQ RIQV RQLA EMQ
Gene ID:51134
Uniprot:Q9Y592
Cellular Location:Cytoplasm, centriole, centrosome, cytoskeleton, microtubule organizing center
Calculated MW:67kDa/82kDa
Observed MW:82kDa
Synonyms:CEP83, CCDC41, NPHP18, NY-REN-58
Background:The protein encoded by this gene is a centriolar protein involved in primary cilium assembly. Defects in this gene have been associated with infantile nephronophthisis and intellectual disability.
UniProt Protein Function:CCDC41: 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 12q22

Cellular Component: centriole; Golgi apparatus; cytosol

Molecular Function:protein binding

Biological Process: vesicle docking; organelle organization and biogenesis; cilium biogenesis

Disease: Nephronophthisis 18

UniProt Code:Q9Y592
NCBI GenInfo Identifier:97045295
NCBI Gene ID:51134
NCBI Accession:Q9Y592.2
Molecular Weight:
NCBI Full Name:Centrosomal protein of 83 kDa
UniProt Protein Name:
UniProt Gene Name:
Anti-CEP83 Polyclonal Antibody (CAB8491)Western blot analysis of extracts of various cell lines, using CEP83 antibody (CAB8491) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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