Cell Biology Antibodies 12

Anti-CEMIP Antibody (CAB8587)

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SKU:
CAB8587
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CEMIP Antibody
Antibody SKU:CAB8587
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 180-420 of human CEMIP (NP_061159.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:A-431, U-87MG, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 180-420 of human CEMIP (NP_061159.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FERS WGHR GVIV HVID PKSG TVIH SDRF DTYR SKKE SERL VQYL NAVP DGRI LSVA VNDE GSRN LDDM ARKA MTKL GSKH FLHL GFRH PWSF LTVK GNPS SSVE DHIE YHGH RGSA AARV FKLF QTEH GEYF NVSL SSEW VQDV EWTE WFDH DKVS QTKG GEKI SDLW KAHP GKIC NRPI DIQA TTMD GVNL STEV VYKK GQDY RFAC YDRG RACR SYRV RFLC GKPV RPKL TVTI DTNV N
Gene ID:57214
Uniprot:Q8WUJ3
Cellular Location:Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane, Nucleus, Secreted, clathrin-coated pit
Calculated MW:110kDa/152kDa
Observed MW:180kDa
Synonyms:CEMIP, CCSP1, HYBID, KIAA1199, TMEM2L
Background:
UniProt Protein Function:CEMIP: May be involved in hearing. Belongs to the TMEM2 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.2.1.35

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: clathrin coated vesicle membrane; cytoplasm; endoplasmic reticulum; extracellular region; plasma membrane

Molecular Function:clathrin heavy chain binding; ER retention sequence binding; hyaluronic acid binding; hyalurononglucosaminidase activity; protein binding

Biological Process: hyaluronan biosynthetic process; hyaluronan catabolic process; positive regulation of cell migration; positive regulation of release of sequestered calcium ion into cytosol; sensory perception of sound

UniProt Code:Q8WUJ3
NCBI GenInfo Identifier:46396475
NCBI Gene ID:57214
NCBI Accession:Q8WUJ3.2
UniProt Secondary Accession:Q8WUJ3,Q6L9J5, Q9H1K5, Q9NPN9, Q9ULM1,
UniProt Related Accession:Q8WUJ3
Molecular Weight:110,357 Da
NCBI Full Name:Cell migration-inducing and hyaluronan-binding protein
NCBI Synonym Full Names:cell migration inducing hyaluronan binding protein
NCBI Official Symbol:CEMIP  
NCBI Official Synonym Symbols:CCSP1; HYBID; TMEM2L; KIAA1199  
NCBI Protein Information:cell migration-inducing and hyaluronan-binding protein
UniProt Protein Name:Cell migration-inducing and hyaluronan-binding protein
Protein Family:Cell migration-inducing and hyaluronan-binding protein
UniProt Gene Name:CEMIP  
UniProt Entry Name:CEMIP_HUMAN
Anti-CEMIP Polyclonal Antibody (CAB8587)Western blot analysis of extracts of various cell lines, using CEMIP antibody (CAB8587) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
Anti-CEMIP Polyclonal Antibody (CAB8587)Immunohistochemistry of paraffin-embedded human lung cancer using CEMIP antibody (CAB8587) at dilution of 1:150 (40x lens).
Anti-CEMIP Polyclonal Antibody (CAB8587)Immunohistochemistry of paraffin-embedded human gastric cancer using CEMIP antibody (CAB8587) at dilution of 1:150 (40x lens).
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