Cell Biology Antibodies 17

Anti-CELF5 Antibody (CAB18482)

(No reviews yet) Write a Review
SKU:
CAB18482
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CELF5 Antibody
Antibody SKU:CAB18482
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human CELF5.
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:U-251MG, U-87MG, Mouse testis
Immunogen:Recombinant protein of human CELF5.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:60680
Uniprot:Q8N6W0
Cellular Location:
Calculated MW:44kDa/52kDa
Observed MW:52kDa
Anti-CELF5 Antibody (CAB18482)Western blot - CELF5 Rabbit pAb (CAB18482)
Synonyms:BRUNOL-5, BRUNOL5, CELF-5, CELF5
Background:This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:CELF5: RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. Belongs to the CELF/BRUNOL family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 19p13

NCBI Summary:This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
UniProt Code:Q8N6W0
NCBI GenInfo Identifier:74762534
NCBI Gene ID:60680
NCBI Accession:Q8N6W0.1
UniProt Secondary Accession:Q8N6W0,O75253, Q59GP2, Q86VW6, Q9BZC0, Q9NR86, D6W614
UniProt Related Accession:Q8N6W0
Molecular Weight:44,479 Da
NCBI Full Name:CUGBP Elav-like family member 5
NCBI Synonym Full Names:CUGBP, Elav-like family member 5
NCBI Official Symbol:CELF5  
NCBI Official Synonym Symbols:CELF-5; BRUNOL5; BRUNOL-5  
NCBI Protein Information:CUGBP Elav-like family member 5
UniProt Protein Name:CUGBP Elav-like family member 5
UniProt Synonym Protein Names:Bruno-like protein 5; CUG-BP- and ETR-3-like factor 5; RNA-binding protein BRUNOL-5
Protein Family:CUGBP Elav-like family
UniProt Gene Name:CELF5  
UniProt Entry Name:CELF5_HUMAN
View AllClose

0 Reviews

View AllClose

Related Products