Anti-Cdx1 Antibody (CAB9546)
- SKU:
- CAB9546
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | Cdx1 Rabbit mAb |
| Product Code: | CAB9546 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Cdx1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HT-29, SGC-7901 |
| Immunogen: | A synthesized peptide derived from human Cdx1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1044 |
| Uniprot: | P47902 |
| Calculated MW: | 28kDa |
| Observed MW: | 28KDa |
| UniProt Protein Function: | CDX1: Could play a role in the terminal differentiation of the intestine. Belongs to the Caudal homeobox family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 5q32 Cellular Component: nucleus Molecular Function:protein binding Biological Process: anterior/posterior axis specification; cell differentiation; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of somitogenesis |
| NCBI Summary: | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47902 |
| NCBI GenInfo Identifier: | 116241291 |
| NCBI Gene ID: | 1044 |
| NCBI Accession: | P47902.2 |
| UniProt Secondary Accession: | P47902,Q4VAU4, Q9NYK8, |
| UniProt Related Accession: | P47902 |
| Molecular Weight: | 14,661 Da |
| NCBI Full Name: | Homeobox protein CDX-1 |
| NCBI Synonym Full Names: | caudal type homeobox 1 |
| NCBI Official Symbol: | CDX1 |
| NCBI Protein Information: | homeobox protein CDX-1 |
| UniProt Protein Name: | Homeobox protein CDX-1 |
| UniProt Synonym Protein Names: | Caudal-type homeobox protein 1 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | CDX1 |
| UniProt Entry Name: | CDX1_HUMAN |
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