Anti-CDH1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0310)
- SKU:
- HDAB0310
- Product Type:
- Rabbit Monoclonal Antibody
- Antibody Type:
- Monoclonal Antibody
- Size:
- 100 μg
- Reactivity:
- Human
- Host Species:
- Rabbit
- Antibody Isotype:
- Rabbit/Human Fc chimeric IgG1
- Clone:
- DMC484
- Synonyms:
- Arc-1, BCDS1, CD324, CDHE, ECAD, LCAM, UVO
Description
system_update_altDatasheet
SKU: | HDAB0310 |
Size: | 100 µg |
Clonality: | Monoclonal |
Clone: | DMC484 |
Synonyms: | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO |
Applications: | Flow Cyt |
Recommended Dilution: | Flow Cyt 1:100 |
Host Species: | Rabbit |
Isotype: | Rabbit/Human Fc chimeric IgG1 |
Reactivity: | Human |
Purification Method: | Purified from cell culture supernatant by affinity chromatography |
Formulation: | Powder |
Buffer: | 1XPBS |
Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
Usage: | Research use only |
Background: | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015] |