Cell Biology Antibodies 12

Anti-CDCA4 Antibody (CAB8736)

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SKU:
CAB8736
Product Type:
Antibody
Applications:
WB
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CDCA4 Antibody
Antibody SKU:CAB8736
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-241 of human CDCA4 (NP_060425.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-241 of human CDCA4 (NP_060425.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MFAR GLKR KCVG HEED VEGA LAGL KTVS SYSL QRQS LLDM SLVK LQLC HMLV EPNL CRSV LIAN TVRQ IQEE MTQD GTWR TVAP QAAE RAPL DRLV STEI LCRA AWGQ EGAH PAPG LGDG HTQG PVSD LCPV TSAQ APRH LQSS AWEM DGPR ENRG SFHK SLDQ IFET LETK NPSC MEEL FSDV DSPY YDLD TVLT GMMG GARP GPCE GLEG LAPA TPGP SSSC KSDL GELD HVVE ILVE T
Gene ID:55038
Uniprot:Q9BXL8
Cellular Location:Nucleus
Calculated MW:26kDa
Observed MW:Refer to figures
Synonyms:CDCA4, HEPP, SEI-3/HEPP
Background:This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1.
UniProt Protein Function:CDCA4: May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation.
UniProt Protein Details:

Protein type:Transcription regulation

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: nucleus

Molecular Function:protein binding

NCBI Summary:This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]
UniProt Code:Q9BXL8
NCBI GenInfo Identifier:32699606
NCBI Gene ID:55038
NCBI Accession:Q9BXL8.1
UniProt Secondary Accession:Q9BXL8,Q8TB18, Q9NWK7,
UniProt Related Accession:Q9BXL8
Molecular Weight:26,114 Da
NCBI Full Name:Cell division cycle-associated protein 4
NCBI Synonym Full Names:cell division cycle associated 4
NCBI Official Symbol:CDCA4  
NCBI Official Synonym Symbols:HEPP; SEI-3/HEPP  
NCBI Protein Information:cell division cycle-associated protein 4
UniProt Protein Name:Cell division cycle-associated protein 4
UniProt Synonym Protein Names:Hematopoietic progenitor protein
Protein Family:Cell division cycle-associated protein
UniProt Gene Name:CDCA4  
UniProt Entry Name:CDCA4_HUMAN
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