Anti-CDC40 Antibody (CAB19794)
- SKU:
- CAB19794
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- EHB3
- Synonyms:
- PRP17
- Synonyms:
- PRPF17
Description
| Product Name: | CDC40 Rabbit mAb |
| Product Code: | CAB19794 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | EHB3, PRP17, PRPF17 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CDC40 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HCT116, HepG2, Mouse lung, Mouse brain, Mouse spleen, Rat lung |
| Immunogen: | A synthesized peptide derived from human CDC40 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 51362 |
| Uniprot: | O60508 |
| Calculated MW: | 74kDa |
| Observed MW: | 75KDa |
| UniProt Protein Function: | CDC40: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.Protein type: Motility/polarity/chemotaxis; RNA processing; RNA splicing; SpliceosomeChromosomal Location of Human Ortholog: 6q21Cellular Component: nucleoplasm; nucleus; spliceosomal complexMolecular Function: protein binding; RNA bindingBiological Process: mRNA 3'-end processing; mRNA export from nucleus; mRNA splicing, via spliceosome; RNA export from nucleus; RNA splicing; termination of RNA polymerase II transcription |
| UniProt Protein Details: | |
| NCBI Summary: | Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60508 |
| NCBI GenInfo Identifier: | 7706657 |
| NCBI Gene ID: | 51362 |
| NCBI Accession: | NP_056975.1 |
| UniProt Secondary Accession: | O60508,O75471, Q5SRN0, Q9UPG1, B2RBC5 |
| UniProt Related Accession: | O60508 |
| Molecular Weight: | 65,521 Da |
| NCBI Full Name: | pre-mRNA-processing factor 17 |
| NCBI Synonym Full Names: | cell division cycle 40 |
| NCBI Official Symbol: | CDC40 |
| NCBI Official Synonym Symbols: | EHB3; PRP17; PRPF17 |
| NCBI Protein Information: | pre-mRNA-processing factor 17 |
| UniProt Protein Name: | Pre-mRNA-processing factor 17 |
| UniProt Synonym Protein Names: | Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17 |
| Protein Family: | Pre-mRNA-processing factor |
| UniProt Gene Name: | CDC40 |
| UniProt Entry Name: |
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