Anti-CD300LB Antibody (CAB20533)
- SKU:
- CAB20533
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CLM7
- Synonyms:
- CLM-7
- Synonyms:
- IREM3
- Synonyms:
- TREM5
- Synonyms:
- CD300b
- Synonyms:
- IREM-3
- Synonyms:
- TREM-5
- Synonyms:
- CMRF35-A2
Description
| Product Name: | CD300LB Rabbit pAb |
| Product Code: | CAB20533 |
| Size: | 50uL, 100uL |
| Synonyms: | CLM7, CLM-7, IREM3, TREM5, CD300b, IREM-3, TREM-5, CMRF35-A2 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human CD300LB (NP_777552.3). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human CD300LB (NP_777552.3). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 124599 |
| Uniprot: | A8K4G0 |
| Calculated MW: | 22kDa |
| Observed MW: | 23KDa |
| UniProt Protein Function: | Function: Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. Ref.1 Ref.9 |
| UniProt Protein Details: | Subunit structure: Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN. Ref.1 Ref.9 Subcellular location: Cell membrane; Single-pass type I membrane protein By similarity. Tissue specificity: Expressed exclusively in myeloid lineages. Ref.1 Post-translational modification: Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2. Sequence similarities: Belongs to the CD300 family.Contains 1 Ig-like V-type (immunoglobulin-like) domain. Sequence caution: The sequence AAH28091.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence BAF83614.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence EAW89170.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. |
| NCBI Summary: | CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | A8K4G0 |
| NCBI GenInfo Identifier: | 510936990 |
| NCBI Gene ID: | 124599 |
| NCBI Accession: | NP_777552.3 |
| UniProt Secondary Accession: | A8K4G0,Q1EG73, Q8IX40, Q8N6D1, |
| UniProt Related Accession: | A8K4G0 |
| Molecular Weight: | 22,689 Da |
| NCBI Full Name: | CMRF35-like molecule 7 |
| NCBI Synonym Full Names: | CD300 molecule-like family member b |
| NCBI Official Symbol: | CD300LB |
| NCBI Official Synonym Symbols: | CLM7; CLM-7; IREM3; TREM5; CD300b; IREM-3; TREM-5; CMRF35-A2 |
| NCBI Protein Information: | CMRF35-like molecule 7; leukocyte mono-Ig-like receptor 5; CD300 antigen like family member B; immune receptor expressed on myeloid cells 3; triggering receptor expressed on myeloid cells 5 |
| UniProt Protein Name: | CMRF35-like molecule 7 |
| UniProt Synonym Protein Names: | CD300 antigen-like family member B; CMRF35-A2; Immune receptor expressed on myeloid cells 3; IREM-3; Leukocyte mono-Ig-like receptor 5; Triggering receptor expressed on myeloid cells 5 |
| Protein Family: | CMRF35-like molecule |
| UniProt Gene Name: | CD300LB |
| UniProt Entry Name: | CLM7_HUMAN |
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