Anti-CD30 Antibody (CAB9789)
- SKU:
- CAB9789
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD30
- Synonyms:
- D1S166E
- Synonyms:
- Ki-1
- Research Area:
- Cell Biology
Description
| Product Name: | CD30 Rabbit mAb |
| Product Code: | CAB9789 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CD30, D1S166E, Ki-1 |
| Applications: | WB, IF |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CD30 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | A-549 |
| Immunogen: | A synthesized peptide derived from human CD30 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 943 |
| Uniprot: | P28908 |
| Calculated MW: | 120kDa |
| Observed MW: | 120KDa |
| UniProt Protein Function: | TNFRSF8: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B. 2 isoforms of the human protein are produced by alternative initiation. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1p36 Cellular Component: cytoplasm; integral to membrane; plasma membrane Molecular Function:transmembrane receptor activity Biological Process: positive regulation of tumor necrosis factor biosynthetic process; negative regulation of cell proliferation; positive regulation of apoptosis; positive regulation of TRAIL biosynthetic process; signal transduction |
| NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P28908 |
| NCBI GenInfo Identifier: | 115978 |
| NCBI Gene ID: | 943 |
| NCBI Accession: | P28908.1 |
| UniProt Secondary Accession: | P28908,Q6P4D9, B1AN79, B9EGD9, D3YTD8, |
| UniProt Related Accession: | P28908 |
| Molecular Weight: | 50,935 Da |
| NCBI Full Name: | Tumor necrosis factor receptor superfamily member 8 |
| NCBI Synonym Full Names: | tumor necrosis factor receptor superfamily, member 8 |
| NCBI Official Symbol: | TNFRSF8 |
| NCBI Official Synonym Symbols: | CD30; Ki-1; D1S166E |
| NCBI Protein Information: | tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30 |
| UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 8 |
| UniProt Synonym Protein Names: | CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen: CD30 |
| UniProt Gene Name: | TNFRSF8 |
| UniProt Entry Name: | TNR8_HUMAN |
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