Cell Biology Antibodies 10
Anti-CCS Antibody (CAB6803)
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- SKU:
- CAB6803
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CCS Antibody |
| Antibody SKU: | CAB6803 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human CCS (NP_005116.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human CCS (NP_005116.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASD SGNQ GTLC TLEF AVQM TCQS CVDA VRKS LQGV AGVQ DVEV HLED QMVL VHTT LPSQ EVQA LLEG TGRQ AVLK GMGS GQLQ NLGA AVAI LGGP GTVQ GVVR FLQL TPER CLIE GTID GLEP GLHG LHVH QYGD LTNN CNSC GNHF NPDG ASHG GPQD SDRH RGDL GNVR ADAD GRAI FRME DEQL KVWD VIGR SLII DEGE DDLG RGGH PLSK ITGN SGER LACG IIAR SAGL FQNP KQIC SCDG LTIW EERG RPIA GKGR KESA QPPA HL |
| Gene ID: | 9973 |
| Uniprot: | O14618 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 29kDa |
| Observed MW: | 37kDa |
| Synonyms: | CCS |
| Background: | Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. |
| UniProt Protein Function: | CCS: Delivers copper to copper zinc superoxide dismutase (SOD1). |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 11q13 Cellular Component: cytoplasm; cytosol; nucleus Molecular Function:copper ion transmembrane transporter activity; protein binding; copper ion binding; zinc ion binding; superoxide dismutase activity; protein disulfide oxidoreductase activity Biological Process: response to reactive oxygen species; removal of superoxide radicals; superoxide metabolic process; intracellular copper ion transport; positive regulation of oxidoreductase activity |
| NCBI Summary: | Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14618 |
| NCBI GenInfo Identifier: | 20137612 |
| NCBI Gene ID: | 9973 |
| NCBI Accession: | O14618.1 |
| UniProt Secondary Accession: | O14618,Q2M366, Q8NEV0, |
| UniProt Related Accession: | O14618 |
| Molecular Weight: | 274 |
| NCBI Full Name: | Copper chaperone for superoxide dismutase |
| NCBI Synonym Full Names: | copper chaperone for superoxide dismutase |
| NCBI Official Symbol: | CCS |
| NCBI Protein Information: | copper chaperone for superoxide dismutase; superoxide dismutase copper chaperone |
| UniProt Protein Name: | Copper chaperone for superoxide dismutase |
| UniProt Synonym Protein Names: | Superoxide dismutase copper chaperone |
| Protein Family: | Capsanthin/capsorubin synthase |
| UniProt Gene Name: | CCS |
| UniProt Entry Name: | CCS_HUMAN |
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