Anti-CCR2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0285)
- SKU:
- HDAB0285
- Product Type:
- Rabbit Monoclonal Antibody
- Antibody Type:
- Monoclonal Antibody
- Size:
- 100 μg
- Reactivity:
- Human
- Host Species:
- Rabbit
- Antibody Isotype:
- Rabbit/Human Fc chimeric IgG1
- Clone:
- DMC447
- Synonyms:
- CC-CKR-2, MCP-1-R, CD192
Description
system_update_altDatasheet
| SKU: | HDAB0285 |
| Size: | 100 µg |
| Clonality: | Monoclonal |
| Clone: | DMC447 |
| Synonyms: | CC-CKR-2, MCP-1-R, CD192 |
| Applications: | Flow Cyt |
| Recommended Dilution: | Flow Cyt 1:100 |
| Host Species: | Rabbit |
| Isotype: | Rabbit/Human Fc chimeric IgG1 |
| Reactivity: | Human |
| Purification Method: | Purified from cell culture supernatant by affinity chromatography |
| Formulation: | Powder |
| Buffer: | 1XPBS |
| Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Usage: | Research use only |
| Background: | The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. |