Cell Biology Antibodies 2
Anti-CCL26 Antibody (CAB11980)
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- SKU:
- CAB11980
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CCL26 Antibody |
| Antibody SKU: | CAB11980 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-94 of human CCL26 (NP_006063.1). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-94 of human CCL26 (NP_006063.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TRGS DISK TCCF QYSH KPLP WTWV RSYE FTSN SCSQ RAVI FTTK RGKK VCTH PRKK WVQK YISL LKTP KQL |
| Gene ID: | 10344 |
| Uniprot: | Q9Y258 |
| Cellular Location: | Secreted |
| Calculated MW: | 10kDa |
| Observed MW: |
| Synonyms: | CCL26, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1 |
| Background: | This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. |
| UniProt Protein Function: | CCL26: Chemotactic for eosinophils and basophils. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family. |
| UniProt Protein Details: | Protein type:Chemokine; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7q11.23 Cellular Component: extracellular space Molecular Function:chemokine activity Biological Process: cell-cell signaling; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; immune response; chemotaxis; signal transduction; inflammatory response; positive regulation of cell migration |
| NCBI Summary: | This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y258 |
| NCBI GenInfo Identifier: | 6685990 |
| NCBI Gene ID: | 10344 |
| NCBI Accession: | Q9Y258.1 |
| UniProt Secondary Accession: | Q9Y258,Q52LV8, A0N0Q5, |
| UniProt Related Accession: | Q9Y258 |
| Molecular Weight: | |
| NCBI Full Name: | C-C motif chemokine 26 |
| NCBI Synonym Full Names: | chemokine (C-C motif) ligand 26 |
| NCBI Official Symbol: | CCL26 |
| NCBI Official Synonym Symbols: | IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha |
| NCBI Protein Information: | C-C motif chemokine 26; eotaxin-3; MIP-4-alpha; chemokine N1; CC chemokine IMAC; thymic stroma chemokine-1; small inducible cytokine A26; small-inducible cytokine A26; macrophage inflammatory protein 4-alpha; small inducible cytokine subfamily A (Cys-Cys), member 26 |
| UniProt Protein Name: | C-C motif chemokine 26 |
| UniProt Synonym Protein Names: | CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1 |
| Protein Family: | C-C motif chemokine |
| UniProt Gene Name: | CCL26 |
| UniProt Entry Name: | CCL26_HUMAN |
 | Immunofluorescence analysis of A549 cells using CCL26 antibody (CAB11980). Blue: DAPI for nuclear staining. |
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