Cell Biology Antibodies 7
Anti-CCL21 Antibody (CAB1896)
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- SKU:
- CAB1896
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CCL21 Antibody |
| Antibody SKU: | CAB1896 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-134 of human CCL21 (NP_002980.1). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-134 of human CCL21 (NP_002980.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SDGG AQDC CLKY SQRK IPAK VVRS YRKQ EPSL GCSI PAIL FLPR KRSQ AELC ADPK ELWV QQLM QHLD KTPS PQKP AQGC RKDR GASK TGKK GKGS KGCK RTER SQTP KGP |
| Gene ID: | 6366 |
| Uniprot: | O00585 |
| Cellular Location: | Secreted |
| Calculated MW: | 14kDa |
| Observed MW: |
| Synonyms: | CCL21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4 |
| Background: | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). |
| NCBI Summary: | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014] |
| UniProt Code: | O00585 |
| NCBI GenInfo Identifier: | 6094386 |
| NCBI Gene ID: | 6366 |
| NCBI Accession: | O00585.1 |
| UniProt Related Accession: | O00585 |
| Molecular Weight: | |
| NCBI Full Name: | C-C motif chemokine 21 |
| NCBI Synonym Full Names: | C-C motif chemokine ligand 21 |
| NCBI Official Symbol: | CCL21 |
| NCBI Official Synonym Symbols: | ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21 |
| NCBI Protein Information: | C-C motif chemokine 21 |
| UniProt Protein Name: | C-C motif chemokine 21 |
| UniProt Synonym Protein Names: | 6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21 |
| Protein Family: | C-C motif chemokine |
| UniProt Gene Name: | CCL21 |
| UniProt Entry Name: | CCL21_HUMAN |
 | Immunohistochemistry of paraffin-embedded human liver using CCL21 antibody (CAB1896) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using CCL21 antibody (CAB1896) at dilution of 1:100 (40x lens). |
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