Cell Biology Antibodies 3
Anti-CAPNS2 Antibody (CAB12394)
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- SKU:
- CAB12394
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CAPNS2 Antibody |
| Antibody SKU: | CAB12394 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CAPNS2 (NP_115706.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:500 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CAPNS2 (NP_115706.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MFLA KALL EGAD RGLG EALG GLFG GGGQ RREG GGRN IGGI VGGI VNFI SEAA AAQY TPEP PPTQ QHFT SVEA SESE EVRR FRQQ FTQL AGPD MEVG ATDL |
| Gene ID: | 84290 |
| Uniprot: | Q96L46 |
| Cellular Location: | Cell membrane, Cytoplasm |
| Calculated MW: | 27kDa |
| Observed MW: | 32kDa |
| Synonyms: | CAPNS2, CSS2 |
| Background: |
| UniProt Protein Function: | CAPNS2: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16q12.2 Cellular Component: cytosol; plasma membrane Biological Process: extracellular matrix disassembly |
| UniProt Code: | Q96L46 |
| NCBI GenInfo Identifier: | 45476965 |
| NCBI Gene ID: | 84290 |
| NCBI Accession: | Q96L46.2 |
| UniProt Secondary Accession: | Q96L46,Q9BPV4, |
| UniProt Related Accession: | Q96L46 |
| Molecular Weight: | 28kDa |
| NCBI Full Name: | Calpain small subunit 2 |
| NCBI Synonym Full Names: | calpain small subunit 2 |
| NCBI Official Symbol: | CAPNS2 |
| NCBI Official Synonym Symbols: | CSS2 |
| NCBI Protein Information: | calpain small subunit 2 |
| UniProt Protein Name: | Calpain small subunit 2 |
| UniProt Synonym Protein Names: | Calcium-dependent protease small subunit 2 |
| Protein Family: | Calpain |
| UniProt Gene Name: | CAPNS2 |
 | Western blot analysis of extracts of mouse brain, using CAPNS2 antibody (CAB12394) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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