Anti-CAPG Antibody (CAB4413)
- SKU:
- CAB4413
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AFCP
- Synonyms:
- HEL-S-66
- Synonyms:
- MCP
- Research Area:
- Cell Biology
Description
| Product Name: | CAPG Rabbit mAb |
| Product Code: | CAB4413 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | AFCP, HEL-S-66, MCP |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CAPG |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse lung, Mouse spleen, Mouse kidney, Rat lung |
| Immunogen: | A synthesized peptide derived from human CAPG |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 822 |
| Uniprot: | P40121 |
| Calculated MW: | 38kDa |
| Observed MW: | 38KDa |
| UniProt Protein Function: | CAPG: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Belongs to the villin/gelsolin family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: F-actin capping protein complex; melanosome; nucleus Molecular Function:actin binding Biological Process: protein complex assembly; cell projection biogenesis; barbed-end actin filament capping |
| NCBI Summary: | This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012] |
| UniProt Code: | P40121 |
| NCBI GenInfo Identifier: | 313104088 |
| NCBI Gene ID: | 822 |
| NCBI Accession: | P40121.2 |
| UniProt Secondary Accession: | P40121,Q53SA7, B8ZZS7, D6W5K8, |
| UniProt Related Accession: | P40121 |
| Molecular Weight: | 348 |
| NCBI Full Name: | Macrophage-capping protein |
| NCBI Synonym Full Names: | capping protein (actin filament), gelsolin-like |
| NCBI Official Symbol: | CAPG |
| NCBI Official Synonym Symbols: | MCP; AFCP; HEL-S-66 |
| NCBI Protein Information: | macrophage-capping protein; macrophage capping protein; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein CAP-G; epididymis secretory protein Li 66 |
| UniProt Protein Name: | Macrophage-capping protein |
| UniProt Synonym Protein Names: | Actin regulatory protein CAP-G |
| Protein Family: | Protein |
| UniProt Gene Name: | CAPG |
| UniProt Entry Name: | CAPG_HUMAN |
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