Immunology Antibodies 2
Anti-CAMK4 Antibody (CAB5304)
- SKU:
- CAB5304
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-CAMK4 Antibody |
| Antibody SKU: | CAB5304 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 304-473 of human CAMK4 (NP_001735.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SW620, U-87MG, Mouse brain, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 304-473 of human CAMK4 (NP_001735.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AANF VHMD TAQK KLQE FNAR RKLK AAVK AVVA SSRL GSAS SSHG SIQE SHKA SRDP SPIQ DGNE DMKA IPEG EKIQ GDGA QAAV KGAQ AELM KVQA LEKV KGAD INAE EAPK MVPK AVED GIKV ADLE LEEG LAEE KLKT VEEA AAPR EGQG SSAV GFEV PQQD VILP EY |
| Gene ID: | 814 |
| Uniprot: | Q16566 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 51kDa |
| Observed MW: | 58kDa |
| Synonyms: | CAMK4, CaMK IV, CaMK-GR, caMK, CaMKIV |
| Background: | The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. |
| UniProt Protein Function: | CAMK4: a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.17; Kinase, protein; CAMK group; CAMK1 family Chromosomal Location of Human Ortholog: 5q21.3 Cellular Component: cytoplasm; cytosol; nucleolus; nucleoplasm Molecular Function:ATP binding; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; calmodulin-dependent protein kinase activity Biological Process: adaptive immune response; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; inflammatory response; innate immune response; long-term memory; myeloid dendritic cell cytokine production; myeloid dendritic cell differentiation; nerve growth factor receptor signaling pathway; nerve-nerve synaptic transmission; nucleocytoplasmic transport; peptidyl-serine phosphorylation; phospholipase C activation; positive regulation of protein export from nucleus; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of osteoclast differentiation; regulation of T cell differentiation in the thymus; signal transduction; synaptic transmission |
| NCBI Summary: | The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16566 |
| NCBI GenInfo Identifier: | 2499586 |
| NCBI Gene ID: | 814 |
| NCBI Accession: | Q16566.1 |
| UniProt Secondary Accession: | Q16566,D3DSZ7, |
| UniProt Related Accession: | Q16566 |
| Molecular Weight: | 51,926 Da |
| NCBI Full Name: | Calcium/calmodulin-dependent protein kinase type IV |
| NCBI Synonym Full Names: | calcium/calmodulin-dependent protein kinase IV |
| NCBI Official Symbol: | CAMK4 |
| NCBI Official Synonym Symbols: | caMK; CaMK IV; CaMK-GR |
| NCBI Protein Information: | calcium/calmodulin-dependent protein kinase type IV |
| UniProt Protein Name: | Calcium/calmodulin-dependent protein kinase type IV |
| UniProt Synonym Protein Names: | CaM kinase-GR |
| Protein Family: | Calcium/calmodulin-dependent protein kinase |
| UniProt Gene Name: | CAMK4 |
| UniProt Entry Name: | KCC4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CAMK4 antibody (CAB5304) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of U2OS cells using CAMK4 antibody (CAB5304). Blue: DAPI for nuclear staining. |
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