Anti-Cadherin 16 Antibody (CAB19644)
- SKU:
- CAB19644
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Product Name: | Cadherin 16 Rabbit mAb |
| Product Code: | CAB19644 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Cadherin 16 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse kidney |
| Immunogen: | A synthesized peptide derived from human Cadherin 16 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1014 |
| Uniprot: | O75309 |
| Calculated MW: | 120kDa |
| Observed MW: | 120KDa |
| UniProt Protein Function: | CDH16: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 16q22.1 Biological Process: cell adhesion |
| NCBI Summary: | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011] |
| UniProt Code: | O75309 |
| NCBI GenInfo Identifier: | 13431340 |
| NCBI Gene ID: | 1014 |
| NCBI Accession: | O75309.1 |
| UniProt Secondary Accession: | O75309,Q6UW93, B4DPA8, H3BPD3, |
| UniProt Related Accession: | O75309 |
| Molecular Weight: | 85,774 Da |
| NCBI Full Name: | Cadherin-16 |
| NCBI Synonym Full Names: | cadherin 16 |
| NCBI Official Symbol: | CDH16 |
| NCBI Protein Information: | cadherin-16 |
| UniProt Protein Name: | Cadherin-16 |
| UniProt Synonym Protein Names: | Kidney-specific cadherin; Ksp-cadherin |
| Protein Family: | Cadherin |
| UniProt Gene Name: | CDH16 |
| UniProt Entry Name: | CAD16_HUMAN |
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