Cell Biology Antibodies 11
Anti-CACNB1 Antibody (CAB7649)
(No reviews yet)
Write a Review
- SKU:
- CAB7649
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CACNB1 Antibody |
| Antibody SKU: | CAB7649 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 429-598 of human CACNB1 (NP_000714.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 429-598 of human CACNB1 (NP_000714.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ATAA LAAS PAPV SNLQ GPYL ASGD QPLE RATG EHAS MHEY PGEL GQPP GLYP SSHP PGRA GTLR ALSR QDTF DADT PGSR NSAY TELG DSCV DMET DPSE GPGL GDPA GGGT PPAR QGSW EDEE EDYE EELT DNRN RGRN KARY CAEG GGPV LGRN KNEL EGWG RGVY IR |
| Gene ID: | 782 |
| Uniprot: | Q02641 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Peripheral membrane protein, sarcolemma |
| Calculated MW: | 53kDa/57kDa/65kDa |
| Observed MW: | 66kDa |
| Synonyms: | CACNB1, CAB1, CACNLB1, CCHLB1 |
| Background: | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. |
| UniProt Protein Function: | CACNB1: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Belongs to the calcium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Channel, calcium Chromosomal Location of Human Ortholog: 17q21-q22 Cellular Component: sarcoplasmic reticulum; T-tubule; voltage-gated calcium channel complex Molecular Function:voltage-gated calcium channel activity; high voltage-gated calcium channel activity Biological Process: synaptic transmission; axon guidance; transport; protein targeting to membrane; neuromuscular junction development |
| NCBI Summary: | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q02641 |
| NCBI GenInfo Identifier: | 20455481 |
| NCBI Gene ID: | 782 |
| NCBI Accession: | Q02641.3 |
| UniProt Related Accession: | Q02641 |
| Molecular Weight: | 57kDa |
| NCBI Full Name: | Voltage-dependent L-type calcium channel subunit beta-1 |
| NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit beta 1 |
| NCBI Official Symbol: | CACNB1 |
| NCBI Official Synonym Symbols: | CAB1; CCHLB1; CACNLB1 |
| NCBI Protein Information: | voltage-dependent L-type calcium channel subunit beta-1 |
| UniProt Protein Name: | Voltage-dependent L-type calcium channel subunit beta-1 |
| UniProt Synonym Protein Names: | Calcium channel voltage-dependent subunit beta 1 |
| Protein Family: | Voltage-dependent L-type calcium channel |
| UniProt Gene Name: | CACNB1 |
| UniProt Entry Name: | CACB1_HUMAN |
 | Western blot analysis of extracts of HepG2 cells, using CACNB1 Antibody (CAB7649) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
