Cell Biology Antibodies 13
Anti-CA5B Antibody (CAB17633)
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- SKU:
- CAB17633
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CA5B Antibody |
| Antibody SKU: | CAB17633 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human CA5B (NP_009151.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, Mouse kidney, Mouse lung, Mouse spleen, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human CA5B (NP_009151.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVVM NSLR VILQ ASPG KLLW RKFQ IPRF MPAR PCSL YTCT YKTR NRAL HPLW ESVD LVPG GDRQ SPIN IRWR DSVY DPGL KPLT ISYD PATC LHVW NNGY SFLV EFED STDK SVIK GGPL EHNY RLKQ FHFH WGAI DAWG SEHT VDSK CFPA ELHL VHWN AVRF ENFE DAAL EENG LAVI GVFL KLGK HHKE LQKL VDTL PSIK HKDA LVEF GSFD PSCL MPTC PDYW TYSG SLTT PPLS ESVT WIIK KQPV EVDH DQLE QFRT LLFT SEGE KEKR MVDN FRPL QPLM NRTV RSSF RHDY VLNV QAKP KPAT SQAT P |
| Gene ID: | 11238 |
| Uniprot: | Q9Y2D0 |
| Cellular Location: | |
| Calculated MW: | 36kDa |
| Observed MW: | 34kDa/36kDa |
 | Western blot - CA5B Polyclonal Antibody (CAB17633) |
| Synonyms: | CA5B, CA-VB |
| Background: | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | CA5B: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. |
| UniProt Protein Details: | Protein type:Energy Metabolism - nitrogen; Mitochondrial; EC 4.2.1.1; Lyase Chromosomal Location of Human Ortholog: Xp21.1 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:carbonate dehydratase activity Biological Process: bicarbonate transport |
| NCBI Summary: | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y2D0 |
| NCBI GenInfo Identifier: | 8928041 |
| NCBI Gene ID: | 11238 |
| NCBI Accession: | Q9Y2D0.1 |
| UniProt Secondary Accession: | Q9Y2D0,A8K4T5, |
| UniProt Related Accession: | Q9Y2D0 |
| Molecular Weight: | 36,434 Da |
| NCBI Full Name: | Carbonic anhydrase 5B, mitochondrial |
| NCBI Synonym Full Names: | carbonic anhydrase 5B |
| NCBI Official Symbol: | CA5B |
| NCBI Official Synonym Symbols: | CA-VB |
| NCBI Protein Information: | carbonic anhydrase 5B, mitochondrial |
| UniProt Protein Name: | Carbonic anhydrase 5B, mitochondrial |
| UniProt Synonym Protein Names: | Carbonate dehydratase VB; Carbonic anhydrase VB; CA-VB |
| Protein Family: | Carbonic anhydrase |
| UniProt Gene Name: | CA5B |
| UniProt Entry Name: | CAH5B_HUMAN |
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