Cell Biology Antibodies 18
Anti-C2orf3 Antibody (CAB18388)
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- SKU:
- CAB18388
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-C2orf3 Antibody |
| Antibody SKU: | CAB18388 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human C2orf3. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human C2orf3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6936 |
| Uniprot: | P16383 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | C2orf3, DNABF, GCF, TCF9, GCFC2 |
| Background: |
| UniProt Protein Function: | TCF9: Factor that represses transcription. It binds to the GC- rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Belongs to the GCF family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 2p12 Cellular Component: nucleoplasm; nucleolus; nucleus Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; spliceosome assembly; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent |
| NCBI Summary: | The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P16383 |
| NCBI GenInfo Identifier: | 318083361 |
| NCBI Gene ID: | 6936 |
| NCBI Accession: | NP_001188263.1 |
| UniProt Secondary Accession: | P16383,O95032, Q53TY0, Q6P2F2, A4UHQ8, A4UHQ9, |
| UniProt Related Accession: | P16383 |
| Molecular Weight: | 28,048 Da |
| NCBI Full Name: | GC-rich sequence DNA-binding factor 2 isoform 2 |
| NCBI Synonym Full Names: | GC-rich sequence DNA-binding factor 2 |
| NCBI Official Symbol: | GCFC2 |
| NCBI Official Synonym Symbols: | GCF; TCF9; DNABF; C2orf3 |
| NCBI Protein Information: | GC-rich sequence DNA-binding factor 2 |
| UniProt Protein Name: | GC-rich sequence DNA-binding factor 2 |
| UniProt Synonym Protein Names: | GC-rich sequence DNA-binding factor; Transcription factor 9; TCF-9 |
| UniProt Gene Name: | GCFC2 |
| UniProt Entry Name: | GCFC2_HUMAN |
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