ChIP Antibodies
Anti-BTNL2 Antibody (CAB7120)
- SKU:
- CAB7120
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BTNL2 Antibody |
| Antibody SKU: | CAB7120 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HepG2, BT-474, HL-60, 293T, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LKVN GPSQ PILV RVGE DIQL TCYL SPKA NAQS MEVR WDRS HRYP AVHV YMDG DHVA GEQM AEYR GRTV LVSD AIDE GRLT LQIL SARP SDDG QYRC LFEK DDVY QEAS LDLK VVSL GSSP LITV EGQE DGEM QPMC SSDG WFPQ PHVP WRDM EGKT IPSS SQAL TQGS HGLF HVQT LLRV TNIS AVDV TCSI SIPF LGEE KIAT FSLS GW |
| Gene ID: | 56244 |
| Uniprot: | Q9UIR0 |
| Cellular Location: | Membrane, Single-pass type II membrane protein |
| Calculated MW: | 19kDa/27kDa/28kDa/30kDa/43kDa/50kDa |
| Observed MW: | 60kDa |
| Synonyms: | BTNL2, BTL-II, BTN7, HSBLMHC1, SS2 |
| Background: | This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. |
| NCBI Summary: | This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. [provided by RefSeq, May 2017] |
| UniProt Code: | Q9UIR0 |
| NCBI GenInfo Identifier: | 73921189 |
| NCBI Gene ID: | 56244 |
| NCBI Accession: | Q9UIR0.1 |
| UniProt Related Accession: | Q9UIR0 |
| Molecular Weight: | 19kDa; 27kDa; 28kDa; 30kDa; 43kDa; 50kDa |
| NCBI Full Name: | Butyrophilin-like protein 2 |
| NCBI Synonym Full Names: | butyrophilin like 2 |
| NCBI Official Symbol: | BTNL2 |
| NCBI Official Synonym Symbols: | SS2; BTN7; BTL-II; HSBLMHC1 |
| NCBI Protein Information: | butyrophilin-like protein 2 |
| UniProt Protein Name: | Butyrophilin-like protein 2 |
| Protein Family: | Butyrophilin-like protein |
| UniProt Gene Name: | BTNL2 |
 | Western blot analysis of extracts of various cell lines, using BTNL2 antibody (CAB7120) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
View AllClose
Related Products
Mouse BTNL2 Recombinant Protein (RPES2071)
system_update_altDatasheetMouse BTNL2 Recombinant Protein Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mo
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human BTNL2 (Butyrophilin-like protein 2) ELISA Kit (HUFI04605)
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीकी
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA Kit
OverviewProduct Name:Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA KitProduct Code:AEFI00360Size:96TAlias:a
