Cell Biology Antibodies 10

Anti-BTG1 Antibody (CAB6359)

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SKU:
CAB6359
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-BTG1 Antibody
Antibody SKU:CAB6359
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-171 of human BTG1 (NP_001722.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-171 of human BTG1 (NP_001722.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ISKF LRTK GLTS ERQL QTFS QSLQ ELLA EHYK HHWF PEKP CKGS GYRC IRIN HKMD PLIG QAAQ RIGL SSQE LFRL LPSE LTLW VDPY EVSY RIGE DGSI CVLY EASP AGGS TQNS TNVQ MVDS RISC KEEL LLGR TSPS KNYN MMTV SG
Gene ID:694
Uniprot:P62324
Cellular Location:
Calculated MW:19kDa
Observed MW:Refer to Figures
Synonyms:BTG1, APRO2
Background:This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
UniProt Protein Function:BTG1: Anti-proliferative protein. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC. Belongs to the BTG family.
UniProt Protein Details:

Protein type:Cell cycle regulation; Oncoprotein

Chromosomal Location of Human Ortholog: 12q22

Cellular Component: cytoplasm; nucleus

Molecular Function:enzyme binding; protein binding

Biological Process: negative regulation of cell proliferation; positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; positive regulation of myoblast differentiation

NCBI Summary:This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
UniProt Code:P62324
NCBI GenInfo Identifier:59799172
NCBI Gene ID:694
NCBI Accession:P62324.1
UniProt Secondary Accession:P62324,P31607,
UniProt Related Accession:P62324
Molecular Weight:19,209 Da
NCBI Full Name:Protein BTG1
NCBI Synonym Full Names:BTG anti-proliferation factor 1
NCBI Official Symbol:BTG1  
NCBI Official Synonym Symbols:APRO2  
NCBI Protein Information:protein BTG1
UniProt Protein Name:Protein BTG1
UniProt Synonym Protein Names:B-cell translocation gene 1 protein
Protein Family:Protein
UniProt Gene Name:BTG1  
UniProt Entry Name:BTG1_HUMAN
Anti-BTG1 Antibody (CAB6359)Immunofluorescence analysis of U2OS cells using BTG1 antibody (CAB6359).
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