Cell Biology Antibodies 12
Anti-BST1 Antibody (CAB9900)
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- SKU:
- CAB9900
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BST1 Antibody |
| Antibody SKU: | CAB9900 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-293 of human BST1 (NP_004325.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-293 of human BST1 (NP_004325.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GARA RWRG EGTS AHLR DIFL GRCA EYRA LLSP EQRN KNCT AIWE AFKV ALDK DPCS VLPS DYDL FINL SRHS IPRD KSLF WENS HLLV NSFA DNTR RFMP LSDV LYGR VADF LSWC RQKN DSGL DYQS CPTS EDCE NNPV DSFW KRAS IQYS KDSS GVIH VMLN GSEP TGAY PIKG FFAD YEIP NLQK EKIT RIEI WVMH EIGG PNVE SCGE GSMK VLEK RLKD MGFQ YSCI NDYR PVKL LQCV DHST HPDC ALKS AAAA TQRK A |
| Gene ID: | 683 |
| Uniprot: | Q10588 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
| Calculated MW: | 29kDa/35kDa |
| Observed MW: | 30kDa |
| Synonyms: | BST1, CD157 |
| Background: | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. |
| UniProt Protein Function: | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. |
| NCBI Summary: | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q10588 |
| NCBI GenInfo Identifier: | 116241273 |
| NCBI Gene ID: | 683 |
| NCBI Accession: | Q10588.2 |
| UniProt Secondary Accession: | Q10588,Q1XII0, Q5U0K0, Q96EN3, B2R6A2, |
| UniProt Related Accession: | Q10588 |
| Molecular Weight: | 29,326 Da |
| NCBI Full Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
| NCBI Synonym Full Names: | bone marrow stromal cell antigen 1 |
| NCBI Official Symbol: | BST1 |
| NCBI Official Synonym Symbols: | CD157 |
| NCBI Protein Information: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
| UniProt Protein Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
| UniProt Synonym Protein Names: | ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD_antigen: CD157 |
| Protein Family: | GPI inositol-deacylase |
| UniProt Gene Name: | BST1 |
 | Western blot analysis of extracts of mouse lung, using BST1 antibody (CAB9900) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of HeLa cells using BST1 antibody (CAB9900) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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