Cell Cycle Antibodies 1

Anti-BORA Antibody (CAB13847)

(No reviews yet) Write a Review
SKU:
CAB13847
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-BORA Antibody
Antibody SKU:CAB13847
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 320-619 of human BORA (NP_079084.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HT-29, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 320-619 of human BORA (NP_079084.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KYSL GSIT SPSP ISSP TFSP IEFQ IGET PLSE QRKF TVHS PDAS SGTN SNGI TNPC IRSP YIDG CSPI KNWS PMRL QMYS GGTQ YRTS VIQI PFTL ETQG EDEE DKEN IPST DVSS PAMD AAGI HLRQ FSNE ASTH GTHL VVTA MSVT QNQS SASE KELA LLQD VERE KDNN TVDM VDPI EIAD ETTW IKEP VDNG SLPM TDFV SGIA FSIE NSHM CMSP LAES SVIP CESS NIQM DSGY NTQN CGSN IMDT VGAE SYCK ESDA QTCE VESK SQAF NMKQ DHTT QRCW MKTA SPFQ CSSP
Gene ID:79866
Uniprot:Q6PGQ7
Cellular Location:
Calculated MW:53kDa/61kDa
Observed MW:90kDa
Synonyms:BORA, C13orf34
Background:
UniProt Protein Function:BORA: Required for the activation of AURKA at the onset of mitosis. Interacts with AURKA. Belongs to the BORA family.
UniProt Protein Details:

Protein type:Activator

Chromosomal Location of Human Ortholog: 13q22.1

Cellular Component: cytosol

Molecular Function:protein binding; protein kinase binding

Biological Process: mitosis; regulation of protein localization; cell division; regulation of mitosis; mitotic cell cycle; G2/M transition of mitotic cell cycle

NCBI Summary:BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008]
UniProt Code:Q6PGQ7
NCBI GenInfo Identifier:74737659
NCBI Gene ID:79866
NCBI Accession:Q6PGQ7.2
UniProt Related Accession:Q6PGQ7
Molecular Weight:61 kDa
NCBI Full Name:Protein aurora borealis
NCBI Synonym Full Names:BORA aurora kinase A activator
NCBI Official Symbol:BORA  
NCBI Official Synonym Symbols:C13orf34  
NCBI Protein Information:protein aurora borealis
UniProt Protein Name:Protein aurora borealis
Protein Family:Protein aurora borealis
UniProt Gene Name:BORA  
UniProt Entry Name:BORA_HUMAN
Anti-BORA Antibody (CAB13847)Western blot analysis of extracts of various cell lines, using BORA antibody (CAB13847) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 40s.
View AllClose

0 Reviews

View AllClose

Related Products