Anti-BIK Antibody (CAB2488)
- SKU:
- CAB2488
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-BIK Antibody (CAB2488) |
| Antibody SKU: | CAB2488 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human BIK (NP_001188.1). |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | Raji |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human BIK (NP_001188.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSEV RPLS RDIL METL LYEQ LLEP PTME VLGM TDSE EDLD PMED FDSL ECME GSDA LALR LACI GDEM DVSL RAPR LAQL SEVA MHSL GLAF IYDQ TEDI RDVL RSFM DGFT TLKE NIMR FWRS PNPG SW |
| Cellular Location: | Endomembrane system, Mitochondrion membrane, Single-pass membrane protein |
| Calculated MW: | 18kDa |
| Observed MW: | 18kDa |
| Synonyms: | BIK, BIP1, BP4, NBK |
| Background: | The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. |
 | Western blot analysis of extracts of Raji cells, using BIK antibody . Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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