Cell Death Antibodies 1
Anti-BCL2L13 Antibody (CAB1109)
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- SKU:
- CAB1109
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-BCL2L13 Antibody |
| Antibody SKU: | CAB1109 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BCL2L13 (NP_056182.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:20 - 1:50 |
| Reactivity: | Human |
| Positive Samples: | HeLa, Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BCL2L13 (NP_056182.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASS STVP LGFH YETK YVVL SYLG LLSQ EKLQ EQHL SSPQ GVQL DIAS QSLD QEIL LKVK TEIE EELK SLDK EISE AFTS TGFD RHTS PVFS PANP ESSM EDCL AHLG EKVS QELK EPLH KALQ MLLS QPVT YQAF RECT LETT VHAS GWNK ILVP LVLL RQML LELT RRGQ EPLS ALLQ FGVT YLED YSAE YIIQ QGGW GTVF SLES EEEE YPGI TAED SNDI YILP SDNS GQVS PPES PTVT TSWQ SESL PVSL SASQ SWHT ESLP VSLG PESW QQIA MDPE EVKS LDSN GAGE KSEN |
| Gene ID: | 23786 |
| Uniprot: | Q9BXK5 |
| Cellular Location: | Mitochondrion membrane, Nucleus, Single-pass membrane protein |
| Calculated MW: | 22kDa/34kDa/52kDa |
| Observed MW: | 48kDa |
| Synonyms: | BCL2L13, BCL-RAMBO, Bcl2-L-13, MIL1 |
| Background: | This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. |
| UniProt Protein Function: | Bcl-2L13: May promote the activation of caspase-3 and apoptosis. Belongs to the Bcl-2 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Apoptosis Chromosomal Location of Human Ortholog: 22q11.1 Cellular Component: mitochondrion; mitochondrial membrane; integral to membrane; nucleus Molecular Function:caspase activator activity Biological Process: caspase activation; apoptosis |
| NCBI Summary: | This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q9BXK5 |
| NCBI GenInfo Identifier: | 23396740 |
| NCBI Gene ID: | 23786 |
| NCBI Accession: | Q9BXK5.1 |
| UniProt Related Accession: | Q9BXK5 |
| Molecular Weight: | |
| NCBI Full Name: | Bcl-2-like protein 13 |
| NCBI Synonym Full Names: | BCL2 like 13 |
| NCBI Official Symbol: | BCL2L13 |
| NCBI Official Synonym Symbols: | MIL1; BCL-RAMBO; Bcl2-L-13 |
| NCBI Protein Information: | bcl-2-like protein 13 |
| UniProt Protein Name: | Bcl-2-like protein 13 |
| UniProt Synonym Protein Names: | Bcl-rambo; Protein Mil1 |
| UniProt Gene Name: | BCL2L13 |
| UniProt Entry Name: | B2L13_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BCL2L13 antibody (CAB1109). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunofluorescence analysis of HeLa cells using BCL2L13 antibody (CAB1109). Blue: DAPI for nuclear staining. |
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